This Project Grant award from the National Science Foundation's Computer and Information Science and Engineering (CISE) program (CFDA 47.070) supports a collaborative research project to investigate the role of brain waves in decision-making and categorization processes. The $1,241,250 award, effective March 1, 2025 through February 28, 2030, will fund research by the Research Foundation for Mental Hygiene, Inc. (RFMH) at the New York Psychiatric Center.
The project aims to leverage computational modeling and neural recordings from humans and animals to better understand how brain rhythms in the prefrontal cortex facilitate flexible decision-making. It tests the hypothesis that shifts in beta frequency oscillations could selectively transmit decision information, akin to frequency-division multiplexing. The research involves close collaboration between computational and experimental neuroscientists to examine the cellular- and circuit-level mechanisms underlying these brain rhythm dynamics and their implications for decision-making processes. The findings could provide insights into brain function relevant to disorders like Parkinson's disease and schizophrenia, where both brain waves and cognitive abilities are impaired.
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