Project Grant 2422620
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) provides $225,000.00 to Carnegie Mellon University and Purdue University to develop a cyberinfrastructure to support the analysis of cryo-electron tomography (cryo-ET) data. The project will build an open-access, annotated database of cryo-ET images, both simulated and experimentally obtained, alongside a toolbox of computational methods for their analysis. This infrastructure will...
- Carnegie Mellon University was awarded a $448,000 project grant from the National Science Foundation Division of Information and Intelligent Systems under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The three-year award will support the development of computational methods and software to enable the systematic de novo identification of macromolecular complexes in cryo-electron tomography images. Specifically, the university will create a...
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $980,943 to Purdue University from August 1, 2025 to July 31, 2029. The project aims to develop new artificial intelligence (AI) tools that can automatically interpret cryogenic electron microscopy (cryo-EM) data into accurate 3D molecular structures and validate those structures for errors. The key objectives are: (1) developing deep learning methods to...
- This Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program, CFDA 47.070, provides $310,000 to the University of Southern California (USC) to develop an innovative training program targeting the materials science research community that relies on advanced microscopes. The key products and services to be delivered through this 3-year project, titled "CITEAM", include training on microscope data processing, the use...
- This Project Grant award in the amount of $380,000 was provided by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) to the University of North Carolina at Chapel Hill (UNC-CH). The purpose of this grant is to develop an innovative training program targeting the materials science research community that relies on advanced microscopes, such as transmission electron microscopes (TEM), for their research....
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded The Trustees of Columbia University in the City of New York a $1,200,000 Project Grant on March 15, 2025 to develop and apply a method of time-resolved cryo-electron microscopy (cryo-EM) to diverse biological molecules of medical importance. The project aims to use newly designed PDMS-based microfluidic chips to apply the time-resolved cryo-EM sample preparation technique, which has been...
- The National Science Foundation (NSF) awarded a $498,240 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to Northeastern University. The grant supports the development of advanced cyberinfrastructure that will enable the findable, accessible, interoperable, and reusable (FAIR) use of single-cell proteomics (SCP) data. SCP is a rapidly emerging field that allows direct measurement of proteins in individual cells. The project will develop open data standards,...
- The National Science Foundation (NSF) awarded a $224,910 Project Grant under the Computer and Information Science and Engineering (CFDA 47.070) program to the University of California, Santa Barbara (UCSB). The grant, effective from September 1, 2024 to August 31, 2027, supports the development of scalable and automated software tools to simulate and analyze "active dynamics" in complex systems, such as flocks of birds, schools of fish, and networks of cells. The project aims to...
- The Project Grant award for "FRAMEWORKS-IMAGING-PHD: EMPOWERING DATA REUSE AND REPRODUCIBILITY THROUGH MICROSCOPY-COMMUNITY-DEFINED PERSISTENT HARDWARE DESCRIPTORS" was provided by the National Science Foundation's Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070). The $3,999,550 award, commencing on August 15, 2025, aims to develop a scalable cyberinfrastructure framework that enables the capture, storage, and dissemination of persistent,...
- The National Science Foundation (NSF) awarded a Project Grant of $599,649 to Carnegie Mellon University (CMU) under the Computer and Information Science and Engineering (CFDA 47.070) program. The goal of this 3-year project, which commenced on April 15, 2024, is to develop perception systems that can infer the 3D structure of generic objects or scenes from 2D images, even with partial observations. Key technical efforts will include formulating mechanisms for learning novel 3D generative...
The National Science Foundation (NSF) awarded a $225,000 Project Grant under the Biological Sciences (CFDA 47.074) program to Carnegie Mellon University and Purdue University. The grant, awarded on August 15, 2025, will support the development of a cyberinfrastructure that enables the analysis of cryo-electron tomography (cryo-ET) data. The project aims to build an open-access, annotated database of cryo-ET images and a robust toolbox of computational methods for their analysis. The resulting resources will lower the entry barrier for new researchers, promote collaboration, and accelerate scientific discoveries across the life sciences. The project also includes educational outreach through interdisciplinary coursework, hands-on research, and workshops at both institutions, as well as for the broader research community, including high school students. The project's intellectual merit lies in establishing a foundational infrastructure for cryo-ET data analysis, which addresses a critical gap in the field.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $225.0k | 7/25/25 |