This $450,000 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to The Johns Hopkins University supports the development of a new "dual-series gate" organic electrochemical transistor (DS-OECT) biosensor technology. The key objectives include material synthesis, device fabrication, computer modeling, and biological fluid analysis to create a highly sensitive and stable sensor capable of reliably detecting protein biomarkers for various medical conditions. The project aims to substantially reduce baseline instability in field-effect transistor biosensors, enabling more accurate biomarker identification. Activities will also involve training students across high school, undergraduate, and graduate levels in multidisciplinary areas like materials science, electronics, computer modeling, and analytical techniques. No subcontracts are planned for this award, which has an ultimate completion date of June 30, 2027.