This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging modalities by providing both deep tissue penetration and high spatial resolution. The project will design transducer molecules that harness ultrasonic waves to trigger NIR chemiluminescence, merging the strengths of ultrasound and optical imaging. This advanced biophotonic imaging system has the potential to significantly enhance medical diagnostics and personalized treatments. The award period runs from May 1, 2024 to April 30, 2026.
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