Project Grant 2345872
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $647,750 Project Grant to Princeton University under the Biological Sciences grant program (CFDA 47.074) to develop a closed-loop control system for regulating microbial communities. The project aims to integrate optogenetic controls and metabolite biosensing to dynamically modulate the composition and productivity of synthetic microbial communities for the production of valuable chemicals. The...
- This $985,496 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the University of Rochester to develop an innovative platform for controlling and stabilizing microbial communities. The project aims to leverage horizontal gene transfer, specifically through plasmid conjugation, to dynamically balance growth rates and community composition, creating programmable microbial populations capable of maintaining stability across...
- The National Science Foundation (NSF) awarded a $949,877 Project Grant to Rutgers, The State University through the Biological Sciences (CFDA 47.074) program. The grant funds a collaborative research project to develop closed-loop control systems that integrate optogenetics and metabolite biosensing to modulate the composition and productivity of synthetic microbial communities. The project aims to advance basic research in this area and generate strategies for improved production of...
- This Project Grant award of $687,304 from the National Science Foundation's Biological Sciences (CFDA 47.074) program will enable the South Dakota School of Mines and Technology to acquire a BioLector XTM microbioreactor system. This specialized equipment can simultaneously grow and monitor up to 48 microbial cultures, replicating large-scale industrial fermentation conditions at a small scale. It will facilitate advanced research across disciplines such as microbiology, biochemical engineering,...
- This Project Grant award, totaling $30,000.00, was provided by the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program to Northwestern University. The award will support collaborative research to investigate the structural and metabolic dynamics of evolutionarily distinct bacterial microcompartments from September 1, 2025 to August 31, 2028. The research aims to provide a generalizable understanding of how bacterial microcompartments, which allow...
- This federal Project Grant award of $820,000 from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research conducted by the University of Delaware to control the spatial arrangement and function of synthetic microbial communities. The key products and services to be delivered under this 3-year award include: Repurposing innovative biological containment tools to direct the self-assembly of specific microbes within a larger synthetic microbial community....
- This $700,000 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports a collaborative research project led by the California Institute of Technology (Caltech) to elucidate and manipulate carbon metabolic niches in soil microbiomes for sustainable agriculture. The project aims to understand the molecular and ecological principles governing soil microbiome composition and function, with the goal of developing strategies to reintroduce and...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $900,000.00 to Colorado State University (CSU) aims to develop a novel microbiome modeling platform. The platform will integrate omics data, thermodynamics principles, metabolic models, and artificial intelligence to unravel the metabolism, interactions, and evolution of microbiomes. This research will be applied to address specific questions regarding the microbiome of a "rewired...
- This National Science Foundation (NSF) Biological Sciences program project grant awarded to William Marsh Rice University (Rice University) in the amount of $800,000 will fund the development of a high-throughput approach to build and study synthetic microbial communities. The project aims to create new methods to rapidly construct and understand the interactions within these complex communities of microbes, with the goal of identifying new sources of antibiotics and providing educational and...
- The National Science Foundation (NSF) Division of Environmental Biology awarded a $291,182 Project Grant to the University System of New Hampshire (UNH), through its University of New Hampshire division operating as the Office of Sponsored Research. The grant, part of NSF's Biological Sciences program (CFDA 47.074), will fund a collaborative research project to evaluate the potential for engineered synthetic microbial communities to help plant hosts, such as duckweed, adapt to the impacts of...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $900,000 to Northeastern University to develop a novel bioreactor system for studying microbial communities. The project, titled "Synthetic Ecology of Mixed Aerobic/Anaerobic Microbial Consortia", aims to create a low-cost, scalable bioreactor platform that can precisely control the atmospheric gas composition across parallel microbial cultures. This system will enable researchers to investigate how variations in oxygen levels impact the dynamics and interactions within synthetic communities of aerobic and anaerobic bacteria, similar to those found in the human gut microbiome. The award supports the establishment of an iGEM team at Northeastern, development of a new K-12 curriculum, and workshops to enhance collaboration between synthetic biologists and the arts/humanities. This first-in-class bioreactor technology, referred to as the Evolver-Atmostat system, has the potential to significantly advance the study of microbial consortia in continuous culture under physiologically relevant conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $900.0k | 6/24/24 |