The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...
This National Science Foundation (NSF) Faculty Early Career Development (CAREER) award under the NSF Engineering (CFDA 47.041) program provides $314,769 to the University of Delaware from February 1, 2025 to January 31, 2030. The project aims to advance fundamental understanding of how cells and tissues communicate information about their mechanical environment, which is critical for advancing treatment strategies for diseases involving tissue stiffening, such as myocardial infarction and...
This $175,000 National Science Foundation project grant supports the development of multi-modal soft tissue characterization technologies for non-invasive breast imaging at the University of Massachusetts Dartmouth from April 2022 through March 2024. Funded under the NSF's Computer and Information Science and Engineering program (CFDA 47.070), the research aims to establish optimization algorithms and parameters for visualizing breast tissue cross-sections non-invasively using an integrated...
This National Science Foundation (NSF) Faculty Early Career Development (CAREER) Program grant, awarded under the NSF Engineering (CFDA 47.041) program, supports research to characterize the mechanical behavior of single cell-cell adhesions. The key products and services to be delivered through this $389,397 award, covering the period from October 1, 2024 to December 31, 2027, include: Quantifying the stress-strain relationship and strain rate-dependent responses of single cell-cell adhesions,...
The National Science Foundation (NSF) awarded a $650,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to the University of Illinois for the development of a bioinspired multispectral imaging sensor to support real-time intraoperative detection of cancer. The award aims to create a novel sensor that integrates perovskite nanocrystals and optical metasurfaces to simultaneously detect endogenous cancer biomarkers in the UV spectrum and exogenous markers...
The National Science Foundation (NSF) awarded a $763,083 Faculty Early Career Development (CAREER) grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to support fundamental research on "Informed Testing - From Full-Field Characterization of Mechanically Graded Soft Materials to Student Equity in the Classroom". The 5-year project aims to establish a method to both cause and quantify 3D deformations inside designed soft materials, reducing the...
This $600,000 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program aims to develop an innovative Optomagnetic Twisting Cytometry (OMTC) system to quantify the dynamic viscoelastic properties of 3D tissue samples. The project will construct an optical scanning system to enable simultaneous measurements of hundreds of thousands of microparticles within a large field-of-view, advancing the understanding of the mechanical properties of live...
This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training Program (CFDA 93.859), provides $526,451 to the University of Maryland, College Park (UMD) to develop a novel optical microscopy technology for high-throughput, non-contact, and non-perturbative cell biomechanics analysis. The key goals are to: Implement technical innovations to significantly increase the acquisition speed of Stimulated Brillouin...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $583,679 to the University of California, Davis (UC Davis) to develop an innovative microscopy system for simultaneously imaging neurons, blood vessels, and other cellular structures within the brain. The project, titled "CAREER: Integrated Multiphoton-Phase Microscopy for Simultaneous and Correlative Imaging of Neurovascular Coupling Dynamics," aims to advance the...