The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain tumor diagnosis, with the potential to advance surgical pathology and image-guided surgery. The goal is to leverage the electric pre-resonance effect of NUV-CARS to achieve significantly enhanced sensitivity for imaging chemical bonds in native biological molecules, enabling rapid label-free imaging of tissue similar to hematoxylin and eosin staining. This research under NSF's Engineering program (CFDA 47.041) will also provide training opportunities in biophotonics and data science for students with diverse backgrounds.
Generated 5/14/24, 10:14 AM