Project Grant 2325819
- The National Science Foundation (NSF) awarded a $460,149 project grant under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) to the University of Massachusetts (UMass) for the development of photoswitchable lipid bilayer membranes. This 3-year project aims to create fully synthetic, lab-made membranes that can mimic the functions of cell membranes, but be powered and driven by light rather than active proteins. The key research goals are to fabricate these...
- This is a $600,000 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Davis. The award supports research investigating the fundamental mechanisms underlying liquid-liquid phase separation and membrane remodeling in cell-like environments. The project aims to quantify the dynamics of phase coarsening, map relationships between intravesicular macromolecular crowding and membrane changes, and...
- The National Science Foundation (NSF) Division of Chemistry has awarded a 3-year, $450,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of California, San Diego (UCSD) to develop and characterize chemistries for generating dissipative phospholipid vesicles (liposomes) that exist in a non-equilibrium state and are sustained by chemical fuel sources. This work aims to better understand the molecular mechanisms underlying dynamic...
- The National Science Foundation (NSF) Chemical Theory, Models and Computational Methods program awarded a $600,000 project grant to Carnegie Mellon University (CMU) to investigate how the asymmetry of cell membranes affects the phase behavior of their lipid constituents. The project, led by Professor Markus Deserno, aims to develop theoretical and computational techniques to elucidate how the asymmetry of cell membranes alters lipid mixing in each leaflet. The research will focus on...
- This is a $260,138 federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049). The grant was awarded to Virginia Polytechnic Institute & State University (Virginia Tech) on September 1, 2024, with a projected completion date of August 31, 2027. The grant funds collaborative research to understand how variations in the molecular composition of lipids and sterols govern the material properties and emergent...
- The National Science Foundation awarded a $538,838 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to The Regents of the University of California, San Francisco for research titled "Collaborative Research: Mapping Protein-Membrane Interactions from Molecules to Cell-Level Dynamics." The research will develop multiscale models to map how individual protein structures and compositions interact with and deform cell membranes at varying scales, from...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $257,697 Project Grant to The Research Foundation for the State University of New York (RF SUNY) to conduct collaborative research on engineering selective membranes from lipid-polyelectrolyte complexes. This 4-year project, which began on October 1, 2025, aims to harness biology-like performance and the chemical versatility of synthetic polymers to develop high-precision membranes for applications such as water...
- This Project Grant award of $654,993 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports research to develop selective membranes from lipid-polyelectrolyte complexes. The goal is to create synthetic membranes that can facilitate the selective separation of specific molecules, enabling applications like clean water production and safe pharmaceutical manufacturing. This interdisciplinary effort combines materials synthesis, molecular simulation, and machine...
- This $208,784 federal Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project to study the emergent dynamics and scaling laws of bioinspired lipid membranes. The University of Arizona, as the primary awardee, will integrate experimental methods such as neutron spectroscopy, NMR, and flicker spectroscopy with molecular dynamics simulations. This integrated approach aims to establish the...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program provides $156,400.00 to the University of Massachusetts (UMass) to conduct research on engineering selective membranes from lipid-polyelectrolyte complexes. The objective is to harness biology-inspired principles to create high-precision synthetic membranes for applications like water purification and pharmaceutical processing, while avoiding the use of toxic...
The National Science Foundation (NSF) awarded a $1,200,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Washington to conduct research on liquid-liquid phase separation in lipid membranes. The 4-year project aims to: 1) test if asymmetric lipid vesicles phase separate similar to flat membranes; 2) develop new methods to determine lipid ratios in coexisting membrane phases and analyze lipid compositions of vesicles; and 3) use Raman imaging and fluorescence microscopy to test theoretical predictions about lipid distributions across membrane phases and boundaries. The research will publish new protocols and computer code, develop scientific teaching materials, and mentor the next generation of scientists. The project contributes to NSF's mission of promoting scientific progress and strengthening the nation's scientific enterprise through basic research on this biologically important phenomenon.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 6/28/23 |