The University of Illinois was awarded a $250,542 project grant from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems to conduct research on the dynamics and stability of multi-component lipid vesicles in flow. The grant falls under the NSF Directorate for Engineering's Engineering program (CFDA #47.041), which supports research and education to improve engineering. The University will use the funding over a two-year period ending...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $232,000 Project Grant to the President and Board of Trustees of Santa Clara College to develop an active lipid vesicle-based drug delivery system. The 3-year grant, starting on September 1, 2023, will leverage the encapsulation capacity of lipid vesicles to enclose both therapeutic payloads and self-propelled particles. This will enable the vesicles to undergo directed...
The National Science Foundation Division of Materials Research awarded a $438,521 project grant to the Georgia Tech Research Corporation from July 1, 2021 to June 30, 2024. The grant supports research titled "Engineering Responsive Chemical Heterogeneity in Protein Vesicles for Simultaneous Delivery of Diverse Cargoes" under the Mathematical and Physical Sciences program (CFDA 47.049). The research aims to develop protein vesicle delivery systems that can encapsulate and release...
The National Science Foundation (NSF) Division of Chemistry has awarded a 3-year, $450,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of California, San Diego (UCSD) to develop and characterize chemistries for generating dissipative phospholipid vesicles (liposomes) that exist in a non-equilibrium state and are sustained by chemical fuel sources. This work aims to better understand the molecular mechanisms underlying dynamic...
This National Science Foundation project grant of $500,000 will fund research at the University of California, Santa Barbara to study the assembly, disassembly, and mechanics of porous colloidal vesicles from April 15, 2023 to March 31, 2026. The research aims to advance understanding of fundamental processes involved in vesicle formation that are relevant across fields including physics, biology, engineering, and materials science. The university researchers will utilize state-of-the-art...
The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded Purdue University a $222,917 Project Grant under the Engineering federal grant program (CFDA 47.041) to support research titled "COLLABORATIVE RESEARCH: DYNAMICS AND STABILITY OF MULTI-COMPONENT LIPID VESICLES IN FLOW" from January 15, 2022 through December 31, 2024. The grant funding will support Purdue University's research exploring the dynamics and stability of...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $200,000 Project Grant to Lutheran University Association Inc., doing business as Valparaiso University, to develop a liposomal drug delivery platform for the treatment of lymphatic filariasis - a neglected tropical disease. The project aims to optimize the lymphatic uptake of existing lymphatic filariasis drugs and improve their efficacy against adult filarial worms. This will be achieved by synthesizing and...
This National Science Foundation (NSF) Engineering Program project grant awarded to the Massachusetts Institute of Technology (MIT) provides $429,384 in funding to study how drug nanoparticles adhered to leukocyte (white blood cell) surfaces influence their mechanical properties and movement through microscale blood vessel networks. The 5-year research effort, from March 2024 to February 2029, will use a combination of biophysical models and microfluidic experiments to generate fundamental...
This National Science Foundation Project Grant of $1,401,652 awarded to the University of Illinois on October 1, 2022 will fund research into hybrid lipid-polymer membranes for ion transport applications under the federal Engineering (47.041) program. The three-year award will support the development of a new class of hybrid materials to precisely control and enhance ion transport at the nanoscale. Researchers will investigate how the nanostructures and domain sizes of block...
The University of Illinois received a $565,222 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering federal grant program (CFDA 47.041). The award will fund research from June 2023 through May 2026 to explore intercellular adhesion as a design parameter for promoting blood vessel formation in engineered or damaged tissues. Specifically, the University will quantify relationships between...