This Project Grant award from the National Science Foundation's (NSF) Division of Information and Intelligent Systems (CFDA 47.070 - Computer and Information Science and Engineering) provides $599,948 to George Mason University, doing business as Mason, to advance algorithmic research at the intersection of information integration and informatics using principled protein language models (PLMs) as computational vehicles. The key objectives of this 3-year project are to: (1) encode prior biological knowledge in PLMs for joint and resource-aware learning in composite spaces, (2) reveal fundamental properties and organize the learned representation space to inform and connect what is captured with properties of interest, and (3) enable PLMs to capture diverse contexts for deeper exploration of the structural, functional, and evolutionary organization across protein space. This interdisciplinary research contributes to the fields of machine learning, bioinformatics, and molecular biology, and provides training opportunities for underrepresented students.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $599.9k | 7/18/23 |