Project Grant 2309859
- The National Science Foundation (NSF) awarded a $125,731 Project Grant to the Kennesaw State University Research And Service Foundation, Inc. (KSU R&SF) on October 1, 2023. The award is funded through the NSF's Engineering program (CFDA 47.041), which supports a wide range of research and development activities to advance engineering knowledge and capabilities. This particular award will tackle the challenge of exploring, analyzing, and interpreting the complex interactions in the tumor...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $575,000 to the New Jersey Institute of Technology (NJIT) will study how the microstructure and interstitial fluid pressure gradient impact cell invasion in a bioprinted tumor-on-a-chip model. The key products and services to be delivered include: Developing a 3D bioprinted tumor spheroid microtissue model with controlled microstructure and tunable fluid-induced pressure. This will involve...
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $529,945 to the New Jersey Institute of Technology under the Engineering program (CFDA 47.041) on July 1, 2026, for a three-year project concluding June 30, 2029. The project will deliver fundamental research and computational tools that establish a quantitative, energy-based framework for predicting tumor invasion as a function of extracellular...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
- This National Science Foundation Project Grant of $299,785 will fund research into the integrated effects of mechanical and biochemical factors on breast tumor invasion and metastasis. Awarded on September 1, 2022 under the Engineering program (CFDA 47.041), the grant supports a collaborative research project led by the University of Michigan from September 1, 2022 through August 31, 2025. Specifically, the research team will develop quantitative imaging biosensors and tissue-engineered breast...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a CAREER grant totaling $538,930 to the University of Alabama in Huntsville, with performance from August 1, 2026, through July 31, 2031. This Engineering program award (CFDA 47.041) funds research and computational modeling to investigate circulating tumor cell (CTC) clusters in the bloodstream and their role in cancer metastasis. The primary...
- This $429,114 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) will fund the development and validation of a first-of-its-kind multi-tissue on-a-chip breast-skin platform. The platform will feature integrated blood and lymphatic vasculature to study the spatial and temporal processes of lymphovascular space invasion (LVSI), dermal lymphatic invasion (DLI), and skin metastasis in breast cancer. The central hypothesis is that the cross-talk...
- The National Science Foundation (NSF) awarded a 5-year, $360,942 CAREER grant to the University of Wisconsin-Milwaukee (UWM) under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070). This grant supports the development of a virtual model of human tumor tissue to enhance understanding of tumor malignancy and advance early diagnosis and treatment of pancreatic ductal adenocarcinoma. The project aims to create a personalized, in-silico model of tumor physiology that...
- This three-year, $681,444 National Science Foundation project grant supports collaborative research to develop tumor-mimetic collagen hydrogels for testing the role of structural cues on cancer cell migration. The Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded the funding under the Engineering program (CFDA 47.041), which aims to foster innovation and excellence in engineering research. The Rochester Institute of Technology will receive the award to create a...
This $487,795 award from the National Science Foundation (NSF) Engineering grant program (CFDA 47.041) supports Arizona State University in developing innovative ex vivo models of the tumor microenvironment (TME). The project aims to mechanistically understand how biophysical cues and signaling between stromal and immune cells contribute to the transition of tumor cells into an invasive phenotype, as well as explore how stromal cell function induces pathway signatures in tumor cells leading to intravasation. The research utilizes tissue engineering, microfluidics, and biomaterials tools to create configurable 3D TME models. In addition to the research goals, the project includes educational objectives such as developing a summer workshop for high school students, creating online video modules, organizing cancer research symposia, and promoting involvement of underrepresented groups. No subawards are planned under this 3-year award which began on October 1, 2023.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $487.8k | 9/11/23 |