Project Grant 2308639

Award Date 10/1/23
Completion Date 9/30/26
Dollars Obligated $300K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Riverside, CA 92521, USA
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The University of California, Riverside (UC Riverside) has been awarded a $300,000 Project Grant from the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation under the CFDA Program 47.041 - Engineering. The grant, titled "COLLABORATIVE RESEARCH: ANALYSIS AND CONTROL OF NONLINEAR OSCILLATORY NETWORKS FOR THE DESIGN OF NOVEL CORTICAL STIMULATION STRATEGIES", aims to develop new theories and tools to predict the onset and spreading of epileptic seizures, and to inform the use of novel electrical brain stimulation strategies to treat neurological disorders. The key products and services to be delivered under this award include:

  1. Characterizing a novel set of dynamical biomarkers that explain changes in neurological recordings during epileptic events, providing a quantitative link between neural mass models and features of epileptic recordings.
  2. Revealing the structural properties that allow healthy, localized neural oscillations to cascade into brain-wide pathological seizures.
  3. Developing spatiotemporal control strategies to regulate the spreading of oscillatory dynamics over networks, providing a theoretical basis to analyze and optimize non-invasive brain stimulation.

This project aims to contribute to the fields of network control, dynamical systems, computational neuroscience, and the development of novel, targeted, non-invasive treatments for neurological disorders. The award period is from October 1, 2023 to September 30, 2026.

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