Project Grant 2305833
- This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
- The National Science Foundation (NSF) awarded a $800,000 Project Grant under its Biological Sciences program (CFDA 47.074) to The Regents of the University of California, doing business as University of California, Berkeley. The grant funding will support collaborative research to discover and characterize compact CRISPR gene editing systems that can be encoded in plant viruses. This will enable more efficient and widespread deployment of genome editing capabilities across a variety of crop...
- This $1,999,998 National Science Foundation Project Grant, funded under the Biological Sciences program (CFDA 47.074), supports research at the University of Washington to advance plant synthetic biology through deciphering the grammar of crop gene regulatory elements. The three-year award beginning March 1, 2023 will apply massively parallel reporter assays and machine learning to characterize tens of thousands of genetic regulatory elements in maize and tomato, including enhancers,...
- The National Science Foundation (NSF) Division of Integrative Organismal Systems awarded a $277,978 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of California, Berkeley. The 3-year grant, beginning on Sep 1, 2023, aims to develop new tools and resources to enable more efficient gene editing in maize, the world's most produced crop. Specifically, the project will generate maize lines that constitutively express the Cas9 gene editing enzyme and engineer...
- This National Science Foundation Project Grant of $921,054 supports research to develop new biological functions through engineering plant hormone receptors. Led by the Regents of the University of California, Riverside under the Biological Sciences program (CFDA 47.074), the project engineers plant sensors to recognize pharmaceuticals and dietary molecules. It then uses these sensors to design "sentinel cells" that indicate molecule presence through color changes. Specifically, the...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $300,000 in funding to Western University of Health Sciences to conduct collaborative research on the variability and regulation of the plant polyadenylation complex. The research aims to better understand how this complex mediates gene expression and plant responses to environmental and developmental cues, with the goal of improving our knowledge of crop plant growth,...
- This National Science Foundation project grant award of $1,004,258 provides funding from February 1, 2022 through January 31, 2025 to support research into perinuclear positioning of active genes in Arabidopsis thaliana. The award is made under the Biological Sciences program (CFDA 47.074) to advance understanding of gene regulation principles in eukaryotes. Specifically, the Regents of the University of California, Riverside will investigate the significance and mechanisms of perinuclear gene...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) federal Project Grant award of $279,000 funds a 3-year postdoctoral research fellowship for Dr. Miles Roberts to study the "Dynamics of K-mers in Low Coverage Population Genetics Data". The research will focus on an inexpensive approach to characterizing genomic variation in plant populations by analyzing patterns of short DNA sequences called k-mers, using the American crop Silphium integrifolium (wild sunflower)...
- This $249,000 National Science Foundation project grant supports research and training in biological sciences from 2024 to 2026. The grant funds a Plant Genome Postdoctoral Fellowship for Samantha Snodgrass at the University of California, Davis under the supervision of Drs. Jeffrey Ross-Ibarra and Graham Coop. The fellowship supports research using population genetics methods to study the domestication of maize and its movement among early farmer communities. Specific aims include estimating...
- This National Science Foundation (NSF) Project Grant award, under the Biological Sciences program (CFDA 47.074), provides $240,000 over three years starting on September 1, 2024 to fund a Postdoctoral Research Fellowship in Biology. The research aims to investigate the effects of bioengineered organisms on community assembly and ecosystem functioning in a soil microbial community. The fellow will use genetic engineering to create microbial consortia and study the impacts on community and...
This $249,000 National Science Foundation project grant funds the development of computational and experimental tools to engineer gene expression in rice. Funded under the Biological Sciences program (CFDA 47.074), the award supports a postdoctoral fellowship held by David Ding at the University of California, Berkeley from July 1, 2023 to June 30, 2026. The fellow will create a pipeline to understand regulatory mutations in plants at scale, coupled with high-throughput experimental assays. A focus on validated gene sets aims to enable simultaneous tuning of multiple target gene abundances through gene editing to additively or synergistically improve traits like photosynthetic capacity, drought resistance, and nitrogen-use efficiency. Findings and any generated data or code will be published and shared publicly for reproducibility and use as tools. This work directly supports the program's goals of strengthening the biological sciences through increased knowledge of challenges facing agriculture.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.0k | 5/12/23 |