This Small Business Innovation Research (SBIR) Phase II Cooperative Agreement award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $999,926 to Nasus Medical, Inc. to develop a novel, miniature spray mechanism for non-invasive nasal drug delivery to treat chronic sinusitis. The project aims to finalize the device design, test it with viscous drug solutions, conduct human factors testing, optimize the design for large-scale...
Nostopharma LLC was awarded a $256,000 Small Business Technology Transfer Phase I Project Grant from the National Science Foundation to develop a sustained-release, biodegradable nanoparticle drug delivery system for treatment of soft tissue trauma complications. Funded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the 12-month project beginning March 1, 2022 aims to demonstrate in vitro and in vivo feasibility of modulating the ectopic bone microenvironment...
Emergency Medical Innovation LLC received a $256,000 Project Grant award from the National Science Foundation to develop a nasal compression device with medicated intranasal sponges for treating nosebleeds. Funded through the NSF's Engineering program (CFDA 47.041), the award will support design and testing of a nasal clip capable of consistently applying proper pressure levels and eluting appropriate doses of medication for nosebleed treatment when placed nominally. Over the one-year period...
Spirrow Therapeutics LLC received a $256,000 Small Business Technology Transfer (STTR) Phase I Project Grant from the National Science Foundation under the Engineering program (CFDA 47.041) to develop polymer surfactant therapy for acute respiratory distress syndrome (ARDS), including that caused by COVID-19. The grant period runs from February 15, 2021 through January 31, 2022. The NSF Engineering program seeks to improve quality of life and economic strength through engineering research and...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant of $274,999 awarded to Materialize Bio, Inc. focuses on developing a novel manufacturing approach for biopolymer-based implantable medical devices, specifically bioengineered tympanostomy tubes. The project aims to create degradable, biocompatible, and antimicrobial tympanostomy tubes using an innovative process involving 3D printed molds, centrifugation, and polymerization. This...
This $962,735 cooperative agreement from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships program (CFDA 47.084) supports the development of an enhanced biodegradable tissue adhesive for gastrointestinal surgical wound closure applications by Bezwada Biomedical LLC. The small business will refine a polyurethane-based adhesive formulation and assess its in vivo performance to identify a safe, easy-to-use lead tissue adhesive that can help prevent anastomotic...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 aims to develop a novel mammalian cell-based nano-biological coating for implantable medical devices. The key objectives are to: (1) characterize nanoparticles produced by different cells on titanium and stainless-steel orthopedic implants, (2) determine the antibacterial, anti-inflammatory, and bone/fibroblast cell growth properties of the coated surfaces, and (3)...
Karios Technologies LLC, a for-profit organization, received a $274,954 SBIR Phase I grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a novel, ready-to-use, large volume delivery system for in situ forming biomaterials. The biomaterials are intended to serve as tissue sealants, scar tissue reducers, and vehicles for drug or cell delivery during surgical procedures. The project aims to transfer a proprietary biomaterial...
The National Science Foundation awarded a $256,000 Small Business Innovation Research Phase I Project Grant to Current Surgical Inc. from May 15, 2021 to November 30, 2021 under the Engineering program (CFDA 47.041). The grant funds the development of a smart needle for precise tumor ablation. The NSF Engineering program supports innovation, creativity, and excellence in engineering research and education to improve quality of life and economic strength. This award advances those goals by...
This Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) provides $1,000,000 in funding to Winter Innovations, Inc. to develop a novel suturing device for orthopedic ligament and tendon surgical procedures. The innovation utilizes a two-part needle technology to improve surgical consistency, reduce procedure times by one-third, and decrease revision rates by nearly two-thirds compared to current...