This $851,000 National Science Foundation project grant supports research and educational activities under the Mathematical and Physical Sciences program (CFDA 47.049) from February 2022 through January 2027. Frederique Deiss of Indiana University-Purdue University Indianapolis will study redox reactions and single particle detection using electrochemiluminescence and microfluidics. The research aims to develop single-entity electrochemistry methods using electrochemiluminescence in droplets...
This Project Grant award, valued at $139,543.00, was made by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049). The funding supports the development of Extended Lifetime Peroxynitrite-Responsive Probes (XL-PRPs), a novel class of reversible biomaterial probes designed for long-term, non-invasive monitoring of oxidative stress biomarkers linked to chronic diseases. Key objectives are to achieve reversible peroxynitrite responsiveness,...
This Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences program (CFDA 47.049) will support Professor Tuhina Banerjee and her team at Missouri State University in developing a series of light-responsive nanoscale enzyme mimics for colorimetric applications. The $249,567 award will fund research to provide fundamental understanding of the physicochemical properties, structure-activity relationships, and reaction kinetics mechanisms of these...
The $209,101 National Science Foundation award under the Mathematical and Physical Sciences program (CFDA 47.049) funds a collaborative research project between North Carolina State University and the University of Miami from September 1, 2023 through August 31, 2026. The project aims to develop a new class of synthetic dyes with photoactivatable fluorescence for bioimaging applications through the synthesis, characterization, and single-molecule spectroscopic analysis of four series of...
The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the University of Utah from August 1, 2023 to July 31, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The funding supports the development of a novel optical biosensor capable of detecting and quantifying a wide range of biological molecules, including biomarkers found in bodily fluids. The project leverages second harmonic generation (SHG) and optical heterodyning techniques...
This $180,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project on electrochemical nickel-catalyzed reductive biaryl coupling. The project, led by researchers at the University of Wisconsin-Madison, University of Missouri-Kansas City, Colorado State University, and NSF, aims to develop new analytical and computational tools to understand the fundamental principles underlying these...
This Project Grant from the National Science Foundation Division of Chemistry, titled "SYNTHESIS, PROPERTIES AND DYNAMICS OF BODIPY-BASED FLUOROPHORES," provides $470,000 in funding from September 1, 2021 to August 31, 2024. The award supports work under the Mathematical and Physical Sciences program (CFDA 47.049) to advance the progress of these sciences and strengthen the Nation's scientific enterprise through increased knowledge and understanding of major problems. Specifically, the...
This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $213,504 to develop new tools for nanoscale chemical and biochemical sensing and imaging. Professor Lane Baker at Texas A&M University will construct new instruments using advanced signal processing and selective chemical and biological sensors to measure very small concentrations of ions, molecules, and proteins at subcellular scales....
This Project Grant award, valued at $231,764.00, was provided by the National Science Foundation's (NSF) Division of Chemistry under the CFDA program "Mathematical and Physical Sciences." The funding supports the University of Illinois Urbana-Champaign's research efforts to establish the fundamental precision bounds of single-molecule spectroscopy within the framework of quantum metrology. Specific focus areas include assessing the limits of spatial resolution for non-photoswitching...
The National Science Foundation (NSF) awarded a 5-year, $430,413 CAREER grant to Wayne State University for a project titled "COMPUTATIONAL DESIGN OF FLUORESCENT PROTEINS WITH MULTISCALE EXCITED STATE QM/MM METHODS." The project, funded under NSF's Mathematical and Physical Sciences (CFDA 47.049) program, aims to advance the understanding and rational design of new fluorescent protein sensors. The research will use classical molecular dynamics, excited state quantum...