This Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049), supports research at the University of Michigan led by Professor Melanie Sanford to study copper, nickel, and iron pincer complexes as catalysts for C-H bond functionalization reactions. The $793,072 award, which runs from May 1, 2024 to April 30, 2028, aims to develop a deeper understanding of first-row transition-metal catalyzed C-H functionalization...
Professor Nathaniel Szymczak of the University of Michigan will use a $525,000 Project Grant award from the National Science Foundation Division of Chemistry to study new strategies for constructing multifunctional catalysts capable of making and breaking carbon bonds. The grant, awarded under the Mathematical and Physical Sciences program (CFDA 47.049), will support the development of transition metal compounds containing multiple reactive sites to advance the basic science needed for...
The National Science Foundation (NSF) Division of Chemistry awarded a 4-year, $680,000 Project Grant to the University of Wisconsin-Madison to develop new "foldamer" catalysts inspired by the structural diversity of enzymes. Under this grant, Professor Samuel H. Gellman will utilize organic and supramolecular chemistries to prepare bifunctional and trifunctional foldamer catalysts capable of promoting carbon-carbon bond forming reactions. The goal is to enable the development of new...
This three-year, $480,000 Project Grant from the National Science Foundation's Division of Chemistry and Mathematical and Physical Sciences program will support the development of sustainable catalysts and dehydrocoupling chemistry at Arizona State University. Principal Investigator Ryan J. Trovitch will study trends in earth-abundant metal catalysts to synthesize value-added chemicals and polymers more efficiently. Initial work will target precursors for semiconductor manufacturing. The project...
This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $221,000 to Professor Karl Scheidt of Northwestern University to develop new catalytic transformations for accessing saturated heterocycles through August 1, 2022 to July 31, 2023. The funding supports research aiming to facilitate access to chiral heterocyclic compounds through new bond-forming reactions, enabling the efficient and...
Under a $595,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program, Professor Thomas Lectka of Johns Hopkins University will pursue two complementary strategies to selectively modify specific carbon-hydrogen or carbon-carbon bonds within complex molecular structures. The first approach will utilize hydrogen bonding to direct site-selective functionalization reactions, while the second will leverage metal ion binding to deactivate...
This $350,000 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry, under the CFDA 47.049 Mathematical and Physical Sciences program, supports a collaborative research effort led by the University of Wisconsin-Madison, University of Missouri-Kansas City, Colorado State University, and University of Missouri to study new approaches to catalysis and electrochemistry for the synthesis of biaryl molecules. The research team will use analytical and computational...
This $700,000 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry (CFDA 47.049 - Mathematical and Physical Sciences) supports a collaborative research project on electrochemical nickel-catalyzed reductive biaryl coupling. The research team from the University of Wisconsin-Madison, University of Missouri-Kansas City, and Colorado State University will use analytical and computational tools to study the fundamental mechanisms and principles underlying these...
This $431,454 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program will support collaborative research led by Professors V. Sara Thoi of Johns Hopkins University and Fanglin Che of the University of Massachusetts, Lowell. The research aims to design and develop new metal-organic catalytic materials for the electrochemical synthesis of commercially valuable organonitrogen compounds, such as urea, acetamide, and...
This National Science Foundation project grant of $300,000 supports research into electrochemical nickel-catalyzed reductive biaryl coupling reactions from May 1, 2022 to April 30, 2025. The award funds a collaborative team from the University of Missouri-Kansas City, the University of Wisconsin-Madison, and Colorado State University under the Mathematical and Physical Sciences program (CFDA 47.049). Specifically, the team will use analytical, computational and electroanalytical tools to study...
This three-year, $502,889 National Science Foundation Division of Chemistry Project Grant supports the development of new modular metal catalysts for tunable carbon-hydrogen (C-H) bond functionalization by Professor Jennifer M. Schomaker of the University of Wisconsin-Madison. Specifically, Professor Schomaker and her team are designing inexpensive silver, iron, and copper catalysts to selectively transform C-H bonds into more valuable carbon-nitrogen (C-N) bonds with high yields. They are applying fundamental research into ligand effects on metal nitrenes and carbenes to establish design principles for non-directed C-H functionalization. Broader impacts include collaborating with industry partners on late-stage drug modifications and employing electrochemical and green solvent methods. This award advances the NSF's Mathematical and Physical Sciences program to strengthen the scientific enterprise through increasing fundamental knowledge and understanding of major problems in chemistry.