This $447,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will support research at Haverford College from December 2022 through February 2026. The research team, led by Dr. Louise Charkoudian, will investigate type II polyketide biosynthetic enzyme assemblies across bacterial species to leverage their capabilities for sustainable chemical production. Undergraduate students will gain research...
The National Science Foundation (NSF) awarded a $339,471 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to Ferris State University to support research on the chemoenzymatic fluorination of aromatic compounds. The project, led by Dr. S. Eric Nybo, aims to develop new enzymatic tools for incorporating fluorine atoms into natural products. The research will involve undergraduate students in studying the biosynthesis of organofluorine molecules, training them in NMR...
Under a $595,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program, Professor Thomas Lectka of Johns Hopkins University will pursue two complementary strategies to selectively modify specific carbon-hydrogen or carbon-carbon bonds within complex molecular structures. The first approach will utilize hydrogen bonding to direct site-selective functionalization reactions, while the second will leverage metal ion binding to deactivate...
This Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $404,662 to Brandeis University to support research exploring novel synthetic approaches for selective functionalization of olefins using stable peroxides. Professor Hao Xu and his students at Brandeis University will develop new iron-catalyzed methods for selective diazidation/diamination and fluoroalkyl transfer reactions on a broad range...
This Project Grant award of $785,000 from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research by Professor Pier Alexandre Champagne at the New Jersey Institute of Technology to advance the chemical understanding of reactive sulfur species. The key products and services to be delivered include: Developing new synthetic donors of reactive sulfur species and using them to probe the behavior of these biochemically important but poorly...
This federal Project Grant award, with a total funding amount of $800,000, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Berkeley. The purpose of the grant is to support research by Professor John F. Hartwig in the Department of Chemistry, who is developing and studying new transition-metal catalyzed reactions to form carbon-fluorine bonds. This research aims to enable the synthesis of a...
This three-year project grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $442,816 to Portland State University to study the intersection of chemical structure, bonding models, and reactivity of hypervalent organohalogens through September 2025. Professors David Stuart and Theresa McCormick will employ combined experimental and theoretical approaches to gain new insights into halogen bonding and the...
The National Science Foundation (NSF) awarded a $214,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to Colby College in Waterville, Maine. The grant supports a research project led by Professor Dasan Thamattoor and his undergraduate student team to investigate the structure and reactivity of reactive chemical intermediates and unusual molecules generated from phenanthrene-based precursors. The research will utilize experimental methods such as photolysis,...
The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $234,925 Project Grant to the University of Florida. The funding supports research conducted by Professor Kate Carroll to investigate post-translational protein cysteine modifications and the chemical reactivity of sulfur. The research explores how different cysteine thiol group modifications impact the properties of the sulfur atom, which is essential for understanding the role...
The National Science Foundation Division of Chemistry awarded $550,000 to the University of Utah under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support research transforming amines into complex polycyclic molecules and natural products from June 1, 2023 to May 31, 2026. Professor Andrew G. Roberts and his research team will develop new synthetic methodology using tertiary amines as templates to iteratively form carbon-nitrogen and carbon-carbon bonds,...