Project Grant 2241312
- This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
- The National Science Foundation awarded a $138,000 Project Grant to support research activities from November 1, 2021 to October 31, 2023 under the Biological Sciences program (CFDA 47.074). The grant funding will enable the grantee to conduct research at the University of Pittsburgh aimed at furthering understanding of the evolution of gene regulatory networks through empirical and theoretical approaches. The Biological Sciences program seeks to advance the field and strengthen the national...
- This Project Grant award of $520,720 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support research to develop new tools for incorporating emerging models of genetics into genetic mapping, prediction, and simulation. The research, conducted by Colorado State University, aims to better integrate molecular and cellular biology knowledge into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype...
- The federal Project Grant award, valued at $697,510.00 and funded by the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program, aims to improve, validate, and interpret amino acid substitution models for protein evolution. The research will enhance understanding of how substitutions of amino acids in proteins impact their form and function, which is critical for reconstructing the evolutionary history of proteins and advancing phylogenetic inference. The project, with a...
- This $332,924 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research at the University of Nebraska from August 2022 to July 2025 investigating convergent evolution of mitochondrial cytochrome c maturation systems in plant and algal species. The research will use molecular biology, genetics, plant growth assays, and computational analysis to study numerous pathway switches and assess the mechanisms and evolutionary importance when there is...
- This $900,000 federal Project Grant award was provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to The Johns Hopkins University. The grant will support research to investigate the mechanistic roles of hyper-divergent regions in gene-by-environment interactions and their impact on adaptation. The project will use cutting-edge genomics, genetic crosses, and high-throughput experiments with nematode species to uncover molecular details on how evolution...
- This $240,000 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) funds a postdoctoral research fellowship to investigate the role of genome organization on de novo gene origination. The research aims to test a new theoretical model explaining the process of new gene evolution, by examining how the genome's structural features influence the birth of genes that arise from non-coding regions. The key components of the research include: 1)...
- This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports a postdoctoral research fellowship to investigate the ecological implications of whole genome duplication in plants. The $240,000 award, effective from September 1, 2024 to August 31, 2027, will enable the fellow to develop new phylogenetic comparative methods to understand how whole-genome duplication impacts climatic niche dynamics. The research will leverage existing...
- This National Science Foundation Project Grant award of $399,383 provides funding from January 1, 2023 through December 31, 2026 to support research at North Carolina State University under the Biological Sciences federal grant program (CFDA 47.074). The award will fund an interdisciplinary research project to integrate data on the evolutionary and migratory potential of the partridge pea plant (Chamaecrista fasciculata) into models forecasting its population dynamics and extinction risk under...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) federal grant program provides $240,000 in funding from January 1, 2025 to December 31, 2027 to conduct research on the evolutionary dynamics of recombination landscapes and adaptive trait architectures across varying degrees of gene flow. The key research objectives are to: (1) generate multiple linkage maps to examine recombination rate as an individual-level phenotype, (2) conduct a...
This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $499,622 to North Carolina State University to develop computational models and analyze genomic data from over 60 species. The researchers will improve existing evolutionary modeling software to infer gene co-evolution networks from comparative genomics of more than a dozen independent polyploidy events. They will identify gene pairs where differences in copy number are evolutionarily costly, indicating dosage interactions. Using large datasets on protein interactions and gene regulation, the researchers aim to understand why certain gene pairs must be maintained at similar copy numbers to function properly. The work seeks to shed light on gene interactions and their relationships to conditions like Down syndrome. The three-year period of performance began January 1, 2023 to further the Biological Sciences program's goals of increasing biological knowledge and understanding major national challenges.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $499.6k | 12/5/22 |