Project Grant 2239665
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $230,000 in funding to the Rochester Institute of Technology (RIT) to advance understanding of articular cartilage, the soft tissue covering the ends of bones in joints. The collaborative research project will examine how cartilage responds to physical forces relevant to daily activities like walking and jumping, with a focus on understanding how it responds to shear forces during...
- This $420,000 Project Grant, awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041), supports a collaborative research project at Cornell University to advance the understanding of articular cartilage and its response to physical forces. The 3-year project, running from June 2025 to May 2028, will integrate theoretical modeling, simulations, and experiments to study how osmotic pressure and different types of mechanical stress, including shear forces,...
- This Project Grant award of $285,630 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will support research at the University of New England (UNE) to elucidate the molecular mechanisms by which articular chondrocytes (cartilage cells) respond to mechanical forces and regulate cartilage health. The goal is to advance the understanding of the pathogenesis of osteoarthritis, a leading cause of joint pain and disability. The research objectives include establishing...
- This National Science Foundation (NSF) CAREER award under the Engineering program (CFDA 47.041) provides $624,622 over 5 years starting September 1, 2025 to support research aimed at advancing the scientific understanding of cartilage microstructure and function. The principal investigator will leverage quantitative magnetic resonance imaging (MRI) techniques to study how changes in the microscopic structure of cartilage impact its macroscopic behavior under loading conditions experienced in...
- The National Science Foundation (NSF) awarded a $335,976 Project Grant under the Engineering CFDA Program (47.041) to the Regents of the University of California, Riverside (UC Riverside) for a 3-year period from October 1, 2023 to September 30, 2026. This grant will fund research to investigate the dynamics of particulate suspensions confined by flexible elastic membranes, which are common in biological micro-scale environments. The project aims to develop a fundamental understanding of the...
- The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...
- The University of California, Merced received a $750,000 National Science Foundation Project Grant under the Engineering program (CFDA 47.041) to support research titled "UNDERSTANDING THE DEFORMABILITY OF BIOLOGICAL FILAMENTS FROM THEIR ATOMISTIC LEVEL DETAILS" from January 1, 2022 through December 31, 2026. The grant will fund research examining the deformability of biological filaments through analysis of their atomic structure to gain a deeper understanding of their material...
- This $539,052 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports fundamental research by North Carolina State University (NC State) to characterize adhesion, friction, and delamination on non-smooth interfaces between soft polymers and functional surfaces. The research aims to elucidate the multiscale mechanisms driving these phenomena, which are critical for a range of engineering innovations in aeronautics, biotechnology, microelectronics,...
- This $424,324 National Science Foundation project grant supports research at the University of Illinois to advance fundamental understanding of the relationship between double network hydrogel microstructure and frictional characteristics. The grant is part of NSF's $47.041 million Engineering research and education program. Specifically, the grant will fund experiments and modeling to elucidate lubrication mechanisms in physically and chemically crosslinked double network hydrogels. Researchers...
- The University of California, Merced received a $200,000 Project Grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation on May 15, 2022 to support research under the Engineering program (CFDA 47.041). The award will fund research from May 15, 2022 through April 30, 2024 to develop multi-scale models of cell-matrix mechanical interactions during endothelial cell network assembly. The Engineering program seeks to improve quality of life and...
This National Science Foundation Project Grant of $523,303 supports research at the University of California, Merced from June 2023 through May 2028 under the Engineering program (CFDA 47.041). The award will fund investigation into the role of fibronectin in mediating the adsorption and retention of synovial fluid components to regulate joint boundary lubrication and wear protection. Specifically, the university researchers will develop articular cartilage surface models, quantify synovial fluid component adsorption, and conduct nanomechanical and nanotribological characterization to establish relationships between fibronectin-mediated synovial fluid film formation and tribological performance. The goal is to better understand load-bearing interfaces like cartilage to identify molecular strategies for treating arthritis and related diseases. Broader impacts include supporting educational and outreach activities involving underrepresented groups in relevant research fields.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $523.3k | 4/6/23 |