Project Grant 2238715
- This $635,000 Project Grant awarded by the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation supports research to understand how mechanical boundary conditions influence tissue assembly and repair in 3D fibrous microtissues. The research aims to advance knowledge about the mechanisms by which mechanical forces regulate new tissue formation and organization, particularly as it relates to wound healing. The project will integrate in vitro experiments and...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
- The University of Massachusetts in Amherst, MA received a three-year, $359,998 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) to conduct research titled "SUBCELLULAR INTERROGATION OF MUSCLE DYNAMICS WITH INTEGRATED OPTOELECTRONIC ARRAYS." The grant aims to advance understanding of muscle dynamics at the subcellular level through development of integrated optoelectronic arrays for interrogating muscle tissue. The Engineering program seeks to...
- The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $399,146 Project Grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to develop a bioreactor system for conducting research on the effects of microgravity and aging on neuromuscular function. The objectives are to evaluate force generation and reactive oxygen species production in tissue-engineered human nerve-muscle constructs,...
- This $600,000 Project Grant award from the National Science Foundation's Division of Information and Intelligent Systems (CFDA #47.070 - Computer and Information Science and Engineering) supports the Massachusetts Institute of Technology (MIT) in developing a cyber physical system to remotely control cellular processes and create synthetic pancreatic tissue. The research aims to overcome challenges in recreating complex 3D tissue structures by using swarms of microrobots to regulate the...
- Federal Project Grant Award Summary The University of Massachusetts received a $650,866 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective June 15, 2025 through May 31, 2030. This project grant supports fundamental research to advance understanding of human neuromotor learning in the context of wearable robotic exoskeleton technology. The research...
- This CAREER award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will provide $314,769 to the University of Delaware to support research advancing the fundamental understanding of how cells and tissue communicate information about their mechanical environment. The project aims to develop new material platforms based on magnetic materials that can dynamically change local tissue stiffness to mimic biological events and measure the resulting mechanobiological...
- Trustees of Tufts College, doing business as Tufts University, was awarded a five-year $534,378 Project Grant from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) beginning September 1, 2023. The grant aims to develop an engineered hybrid brain tissue model that integrates functional neuronal networks with bioelectronic devices. Specifically, Tufts University researchers will create a bioelectronic mesh capable of multiplexed stimulation and recording of neuronal...
- This $995,498 National Science Foundation project grant supports research at the University of California, Los Angeles to advance knowledge of cellular mechanobiology and translate findings for sustainable protein production. Funded through the NSF's Engineering program (CFDA 47.041), the research aims to understand how cells sense and respond to mechanical stimuli by building a systems-level understanding of the "mechanome." Specific goals include investigating predicted mechanical...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $249,894 to the New York Institute of Technology (NYIT) to establish a comprehensive computational framework for hierarchical modeling of skeletal muscles. The project aims to advance the fundamental understanding of skeletal muscle biomechanics by integrating knowledge from computational methods, constitutive mathematical models, microstructural intricacies,...
This five-year, $649,659 National Science Foundation Engineering Project Grant will support research at the Massachusetts Institute of Technology to advance fundamental understanding of the tissues that produce voluntary movement in humans and other biological creatures. Specifically, the grant will fund experiments studying how mechanical signaling coordinates assembly, maturation and repair at the neuromuscular interface in both physiological and pathological states. The principal investigator will develop new model systems using biofabrication tools and protocols to build complex three-dimensional neuromuscular tissues from living cells. These engineered models could enable high-throughput testing of new therapies and deployment as adaptive actuators in soft robotics. The award also includes educational and outreach goals promoting hands-on training in biofabrication for K-12 and adult learners. This project aims to establish the foundation for the principal investigator's long-term career in biofabrication while advancing knowledge in mechanics and biology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $649.7k | 4/5/23 |