This National Science Foundation Project Grant of $605,170 will fund research into the biocompatibility of nanoparticles implanted intradermally as minimally invasive medical devices. Awarded on September 1, 2023 under the Engineering program (CFDA 47.041), the five-year project will be performed by the University of Colorado Boulder.
The grantee will create a library of nanoparticles varying in size, composition, density and stiffness for implantation in murine dermal tissue. Biocompatibility will be characterized in vivo with respect to immunogenicity, toxicity and biodistribution. Outcomes from an art-meets-science workshop will explore connections between body art and biomedical engineering. This foundational research aims to establish guidelines ensuring the safety of tattoo pigments and next-generation intradermal biomedical nano-implants.
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