Project Grant 2230243
- This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $309,974 to support the development of a novel, low-cost device called LIVERscope. The LIVERscope device uses advanced magnetic resonance (MR) technology to noninvasively estimate quantitative biomarkers of nonalcoholic fatty liver disease (NAFLD), including liver...
- This Project Grant, awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop fat and iron-corrected quantitative MRI T1 mapping techniques for evaluating chronic liver disease. Specifically, the $830,401 grant awarded to New York University will investigate the use of MRI markers, including proton density fat fraction, T2*/R2*, and MR elastography, to...
- This $200,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research effort led by New York University (NYU) School of Medicine. The project aims to enhance the design of fluorinated protein fibers and hydrogels for medical applications. Key objectives include: 1) generating coiled-coil fluorinated fibers for controlled drug delivery, 2) developing temperature-responsive fluorinated hydrogels,...
- This National Science Foundation (NSF) Project Grant award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 in funding to Nanores LLC for the development of a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues at nanoscale resolution and depths up to 250 micrometers. The project aims to advance fluorescence imaging capabilities to enable breakthroughs in drug discovery, disease...
- The National Science Foundation (NSF) awarded a $1,125,000 Project Grant to Case Western Reserve University's Office of Research Administration Division (doing business as University Hospitals of Cleveland) under the NSF's Computer and Information Science and Engineering (CFDA 47.070) program. The grant, awarded on September 1, 2023 and scheduled for completion on August 31, 2027, supports the development of an artificial intelligence-generated virtual contrast magnetic resonance imaging (MRI)...
- This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $300,000 to New York University (NYU) to enhance the design of fluorinated protein fibers and hydrogels for medical applications. The key objectives are: 1) generating coiled-coil fluorinated fibers for controlled drug delivery, 2) developing fluorinated coiled-coil hydrogels that change with temperature, and 3) assessing the potential of these materials as...
- The National Science Foundation awarded Nanoxort LLC a $256,000 Project Grant under the Engineering federal grant program (CFDA 47.041) for the period of March 15, 2021 through February 28, 2022. The grant funds the development of a novel size-changing, gadolinium-free contrast agent for magnetic resonance angiography. The Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in engineering research. This award supports Nanoxort's...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $686,484 Project Grant to The Research Foundation for the State University of New York (RF-SUNY) operating as RF-SUNY at the University at Albany. The funding will enable the development and employment of label-free Raman spectral imaging and transport of intensity equation optical diffraction tomography (TIE-ODT) to visualize and quantify the distribution of iron-binding proteins, such as ferritin and transferrin,...
- This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $275,000 to Ubiquitx Inc., a New York-based small business, to develop a programmable, modular therapeutic platform for the direct modification of proteins of interest (POIs) using artificial intelligence, protein engineering, and mRNA therapeutics. The goal is to expand the applications of the company's Chimeric Ligands for Induced Proximity (CLIPS)...
This National Science Foundation Project Grant of $100,000 supports the development of a self-assembling, protein-based contrast agent targeted to collagen type 1 for non-alcoholic fatty liver disease diagnosis and monitoring. Funded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the award to New York University will support research and innovation leading to a breakthrough biomedical imaging technology. Specifically, the university will develop a recombinant protein called COL1-TRAP that forms hierarchical micelles capable of binding to collagen deposits in the liver. By tracking collagen type 1 deposition noninvasively, the contrast agent technology seeks to improve NAFLD diagnosis and monitoring compared to invasive biopsy methods currently used. The targeted, multivalent structure of the COL1-TRAP assemblies is designed to provide high-affinity, specific imaging of fibrosis as the disease progresses. Completion is scheduled for June 2023.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $50.0k | 6/28/22 |