This $255,706 National Science Foundation SBIR Phase I Project Grant to Metfora LLC supports the development of a novel multiplexed metabolite diagnostic blood test for early detection of chronic diseases. The NSF Technology, Innovation, and Partnerships program aims to advance science and engineering solutions to national challenges through innovation and partnerships.
Specifically, Metfora will use mass spectrometry and artificial intelligence to analyze specific panels of circulating metabolites indicative of cellular changes that occur early in diseases. The technology has potential to reduce diagnostic time intervals from years to weeks or days and alter more invasive procedures. Initial work will focus on establishing reproducible mass spectrometry methods and calibrated values for pulmonary arterial hypertension detection. Multi-label classifications will also account for co-morbidities' effects on overall metabolic changes. The one-year project launches in February 2023 to advance this non-invasive diagnostic technology's commercial potential.
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