Project Grant 2204027

Award Date 8/1/22
Completion Date 7/31/25
Dollars Obligated $271K
Funding Federal Agency
Office of Integrative Activities
Awarding Federal Agency
Division of Materials Research
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Omaha, NE 68182, USA
Similar Awards
The National Science Foundation awarded North Carolina State University $525,836 under the Mathematical and Physical Sciences program (CFDA 47.049) for a three-year project grant completing July 2025. The university will research self-organizing nucleic acid supramolecular assemblies with stimuli-responsive properties. Specifically, the project aims to develop a toolkit for constructing responsive nanoparticle-based materials using rationally designed RNAs as modular building blocks. Researchers...
This Project Grant award, provided by the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083), will support the development and experimental validation of computational tools for designing DNA nanostructures and molecular systems. The $300,000 grant, awarded on February 1, 2025 with a project duration through January 31, 2027, aims to create novel multiscale modeling frameworks that integrate high-level and low-level simulations to predict the behavior of engineered...
This $236,662 National Science Foundation award through the Mathematical and Physical Sciences program (CFDA 47.049) funds research at Emory University to develop novel biomimetic materials capable of simultaneously encoding both nucleic acid and protein information codes to control assembly and function. Specifically, the award supports exploration of "bilingual biopolymers" using peptide nucleic acid as a scaffold to direct structure based on both peptide and nucleic acid...
The University of California, San Diego will deliver a project titled "Responsive Materials from Self-Assembling Nucleic Acid Nanoshapes" through a $535,012 Project Grant from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049). The three-year award running from July 2021 to June 2024 will support research into developing responsive materials using self-assembling nucleic acid nanostructures. The Mathematical and Physical Sciences...
This National Science Foundation (NSF) Project Grant award, funded under the Integrative Activities program (CFDA 47.083), supports research on the structural mechanisms of bacterial extracellular DNA-recognition. The $216,149 award to the Board of Regents of the University of Nebraska, from July 1, 2023 to June 30, 2026, aims to identify and characterize novel DNA receptor subunits incorporated into bacterial surface appendages. The project will purify soluble protein constructs, measure...
This Project Grant award of $202,300 from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports computational modeling research at Creighton University. Principal Investigator Dr. Makenzie Long and undergraduate students will use molecular dynamics simulations to investigate how divalent metal ions mediate DNA adsorption to functionalized surfaces. The project aims to elucidate the mechanisms underlying ion-specific effects on DNA self-assembly...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $397,494 to the University of Colorado, awarded on January 1, 2025, will fund research to study the fundamental relationships that control the assembly of solid materials from many small, shape-changing ribbon-like particles made of liquid crystal elastomers. The research aims to enable porous synthetic materials that self-assemble on command and have tunable mechanical properties and porosity, with...
The Board of Regents of the University of Nebraska received a $649,999 Project Grant award from the National Science Foundation Division of Molecular and Cellular Biosciences on August 15, 2021 to support research titled "Nanoscale Structure and Dynamics of Nucleosome Arrays Assembled on DNA Templates with Physiologically Relevant Sequences." The award is part of the NSF's Biological Sciences program (CFDA #47.074), which aims to promote progress in the biological sciences and...
The National Science Foundation (NSF) awarded the University of New Mexico (UNM) a $500,000 Project Grant under the Computer and Information Science and Engineering (CFDA 47.070) program. The grant supports research on the design of heterochiral DNA nanostructures for biomaterials applications. The project aims to study the structure and function of these hybrid DNA materials that combine right-handed (D-DNA) and left-handed (L-DNA) forms, and to use computational modeling and experimental...
This Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), in the amount of $642,000, will fund research at Northwestern University to develop novel hybrid protein-DNA supramolecular structures. The key objectives are to: (1) design generalizable strategies for site-specific DNA functionalization to control proteins in 1D arrays; (2) create dynamic, DNA-driven 2D protein lattices; and (3) utilize DNA interactions to facilitate...

This National Science Foundation project grant award of $270,728 provides funding from August 1, 2022 through July 31, 2025 to support research exploring self-organization of functional nucleic acid supramolecular assemblies with stimuli responsive properties. Funded under the NSF Integrative Activities program (CFDA 47.083), the award supports the University of Nebraska at Omaha and its parent institution, the Board of Regents of the University of Nebraska, in developing a toolkit for constructing stimuli-responsive nanoparticle-based materials designed for end users in biotechnology. Specifically, the project aims to advance understanding of how to correlate programmable parameters of nucleic acid nanoparticles with the physicochemical and mechanical properties of their supramolecular assemblies. It will also evaluate functionalizing individual nanoparticles with inorganic nanomaterials and investigate the effect of stimuli-dependent kinetic pathways on functional supramolecular assembly properties. Outcomes will substantially advance frameworks for engineering nucleic acid nanoparticle supra-assemblies as novel stimuli-responsive biomaterials enabling broad application in biomedical, electronic, and imaging fields.

Generated 1/7/24, 12:40 AM