The National Science Foundation (NSF) Division of Chemistry awarded a $468,099 Project Grant to the University of Connecticut (UConn) under the Mathematical and Physical Sciences (CFDA 47.049) program. The grant supports the development of new strategies to synthesize synthetic polypeptides, or artificial protein-like polymers, under metal-free, auto-catalyzed conditions. This research, led by Dr. Yao Lin, aims to enable more efficient and finely controlled synthesis of these polypeptides,...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports Professor Timothy Newhouse of Yale University's research on developing computational strategies for the synthesis of complex natural products, specifically focusing on diterpenoids. The $600,000 award over a 3-year period from June 2025 to May 2028 will fund the development of AI-based tools to predict the yield of key carbon-carbon bond forming reactions and...
This Project Grant from the National Science Foundation Division of Chemistry provides $500,000 to New York University from August 1, 2021 through July 31, 2024 to support research titled "Towards a Greener Approach for Chemical Synthesis of Peptides." The award is part of the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise through increasing knowledge and enhancing...
This $559,842 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry under the CFDA Program 47.049 - Mathematical and Physical Sciences supports the development of theoretical models and computational data analysis tools by Dr. Dmitrii E. Makarov of the University of Texas at Austin. The research aims to decipher the fundamental mechanisms of biomolecular motions and the efficiency of molecular machines through a synthesis of chemical theory, computational...
This $271,440 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports Professor Filippo Romiti at the University of Texas at Dallas (UTD) in developing new chemical methods and synthesis strategies for the preparation of biologically active heterodimeric natural products. The key objectives of this 5-year grant are to: 1) investigate a novel catalytic chemoselective amide reduction/Friedel-Crafts process to directly...
The National Science Foundation (NSF) Division of Chemistry awarded a $570,000 Project Grant to the University of Texas at Austin (UT Austin) under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new supramolecular systems that exhibit stimulus-responsive changes in electronic structure, ion recognition, and self-assembly. The 3-year award, effective November 1, 2023, will support research by Professor Jonathan L. Sessler and coworkers to investigate the influence of...
This $550,000 Project Grant award, provided by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program, supports Professor Jon Njardarson of the University of Arizona in developing new chemical reaction cascades. The goal is to leverage readily available feedstock materials and negatively charged reaction partners to efficiently produce higher-value fine chemical products. Key focus areas include in-situ trapping of lithium...
This $640,000 Project Grant award from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program, supports a collaborative research effort between Professors Wooley and Darensbourg of Texas A&M University. The objective is to develop sustainable synthetic methodologies that harness the chemical diversity of natural products to produce next-generation macromolecular materials. The proposed work aims to...
This Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports research at the University of Texas at San Antonio (UTSA) focused on developing new catalytic methods for constructing important chemical building blocks. The $463,709 award, which began on April 1, 2025, will enable UTSA professors Oleg Larionov and Michael Doyle, in collaboration with French researchers Nicolas Blanchard and...
This $575,000 Project Grant award from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Berkeley will support Professor Thomas Maimone's research on developing new synthetic strategies for constructing complex, nitrogen-containing molecules. The work aims to identify transformations that can efficiently produce unique target molecules with potential applications in pharmaceuticals, agrochemicals, and materials. The...