Project Grant 2202743
- This Project Grant award from the National Science Foundation's Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program supports a collaborative research effort led by Emory University and the University of Illinois Chicago to design and develop peptide-based filamentous nanomaterials. The $300,000 award, effective from August 1, 2024 to July 31, 2027, will leverage computational methods to systematically explore the energetics and structural designability of...
- This $236,662 National Science Foundation award through the Mathematical and Physical Sciences program (CFDA 47.049) funds research at Emory University to develop novel biomimetic materials capable of simultaneously encoding both nucleic acid and protein information codes to control assembly and function. Specifically, the award supports exploration of "bilingual biopolymers" using peptide nucleic acid as a scaffold to direct structure based on both peptide and nucleic acid...
- The National Science Foundation, through its Division of Chemistry and the Mathematical and Physical Sciences program (CFDA 47.049), awarded a $577,690 Project Grant to the University of North Carolina at Chapel Hill from July 1, 2023 through June 30, 2027. The grant supports research to characterize the biosynthetic pathways of dehydroamino acids in nonribosomal peptides, which are biologically and industrially important natural products. The research aims to understand the molecular details of...
- The National Science Foundation Division of Chemistry awarded a $531,000 Project Grant to the University of California, Santa Barbara for research titled "Assembly and Peptide Cross Talk in Amyloid Systems." The grant period runs from July 1, 2021 to June 30, 2024. The research aims to advance understanding of major problems in the Mathematical and Physical Sciences program area by investigating amyloid assembly and interactions at the molecular level. Specifically, the university will...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) supports research to develop synthetic biomaterials that mimic communication and information exchange in living systems. The $641,052 award to Emory University is focused on studying how intrinsically disordered materials can self-assemble into functional "coacervate" structures that exhibit emergent properties, such as molecular...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $441,848 to the University of California, Santa Barbara to conduct research on the fundamental science of "complex coacervates", which are microscopic droplets formed from charged polymers. The research aims to develop a mechanistic understanding of how these materials form and their unique properties, such as the ability to encapsulate and deliver...
- Under a $579,743 National Science Foundation Project Grant awarded July 1, 2023 through June 30, 2026, the University of California, Los Angeles will provide research services through its Chemistry Department in support of the agency's Mathematical and Physical Sciences program (CFDA 47.049). Specifically, Professor Patrick Harran and colleagues will develop new synthetic tools and methods to create a novel class of fluorinated cyclic peptide compounds, studying their three-dimensional...
- The National Science Foundation (NSF) has awarded a $250,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Merced. The grant, titled "LEAPS-MPS: EXPANDING THE PEPTIDE ASSEMBLY LANDSCAPE USING MULTIVALENT PEPTIDE MACROCYCLES WITH DESIGNABLE INTERMOLECULAR INTERFACES", supports research led by Professor Merg and his students aimed at developing new approaches for designing and constructing peptide-based nanomaterials....
- The University of California, Los Angeles (UCLA) received a $800,000 Project Grant from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program, beginning on September 1, 2024 and continuing through August 31, 2027. The grant supports a project by Professors Diaconescu and Alexandrova to develop redox switchable polymerization catalysts for generating biodegradable copolymers. Their research combines machine learning with experimental approaches to design...
- This $401,000 Project Grant awarded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will support research at the University of California, Irvine (UCI) to fundamentally understand the structure, dynamics, and encapsulation behavior of multiphase amphiphilic block copolymers in solution. The project aims to establish robust relationships between polymer structures, solution conditions, and phase behaviors through advanced characterization techniques. It will also...
This National Science Foundation project grant award of $487,779 provides funding from July 1, 2022 to June 30, 2025 to support research on the synthesis, assembly, and properties of dehydroalanine-containing block copolypeptides. Professor Timothy J. Deming of the University of California, Los Angeles will prepare and study the aqueous self-assembly of synthetic copolypeptide amphiphiles containing dehydroamino acids. The goal is to understand how the extended conformation of hydrophobic dehydroalanine segments influences assembly structure and to subject the synthesized polymers to chemical modifications mimicking biological conditions in the human body. This work has the potential to advance knowledge of self-assembly of complex biopolymers and the development of stimuli-responsive biomaterials for therapeutic delivery applications. The funding also supports interdisciplinary training of graduate and undergraduate students, including opportunities for underrepresented groups. The award is provided through the NSF's Mathematical and Physical Sciences program, which aims to strengthen the nation's scientific enterprise through increasing scientific knowledge and understanding of major problems.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $487.8k | 5/6/22 |