This Project Grant award of $550,000 from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports Professor Sarah Reisman of the California Institute of Technology (Caltech) in developing new catalytic reactions for the chemical synthesis of natural products. The research aims to advance the state-of-the-art in catalytic carbon-carbon bond formation and demonstrate how modern synthetic methods can...
The National Science Foundation awarded a $500,000 Project Grant to the California Institute of Technology under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support the development of new transition metal-catalyzed reaction methods for synthesizing alkaloids with anticancer properties. Professor Brian Stoltz and his team at Caltech will utilize palladium-catalyzed reactions to rapidly construct the complex molecular frameworks of targeted marine-derived chemical...
This $200,000 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) program will support a postdoctoral research fellowship under the mentorship of Dr. Sarah Reisman at the California Institute of Technology (Caltech). The fellowship, awarded to Dr. Kristen Gardner, aims to develop a novel dual ligand nickel-catalyzed system for enantioselective cross-coupling reactions using unactivated alkyl chlorides. This research seeks to address...
This National Science Foundation (NSF) award, under the Mathematical and Physical Sciences (CFDA 47.049) program, provides $575,000 to the University of California, Davis (UC Davis) to study the development of new silicon-based molecules and their use as catalysts for efficient organic synthesis and renewable polymer production. The 3-year project, led by Professor Annaliese Franz, aims to design innovative multi-functional silanol ligands with unique properties that can enable the creation of...
This $525,000 National Science Foundation project grant supports research at the University of California, Irvine to develop new nickel-catalyzed stereospecific cross-electrophiile coupling reactions from 2022-2025. Professor Elizabeth Jarvo and her team are studying nickel catalysis mechanisms to establish ligand features necessary to support one- and two-electron redox steps in cross-electrophiile coupling reactions. Their work seeks to provide useful late-stage functionalization strategies...
This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $221,000 to Professor Karl Scheidt of Northwestern University to develop new catalytic transformations for accessing saturated heterocycles through August 1, 2022 to July 31, 2023. The funding supports research aiming to facilitate access to chiral heterocyclic compounds through new bond-forming reactions, enabling the efficient and...
This Project Grant award, provided by the National Science Foundation's (NSF) Division of Chemistry under the CFDA program for Mathematical and Physical Sciences, supports research conducted by Dr. Kevin Kou at the University of California, Riverside. The $770,000 grant, awarded on July 1, 2024, aims to develop new chemical reactions that streamline the preparation of molecules relevant to the pharmaceutical and agrochemical sectors, including those derived from nature. The research focuses on...
This $725,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports Professor Kay M. Brummond of the University of Pittsburgh in developing a predictive model for catalyzing the asymmetric Pauson-Khand reaction, a powerful organic synthesis technique. Through a collaboration with Merck, Inc., this 3-year project will leverage scientific expertise and infrastructure to create opportunities for designing more targeted and...
This $575,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project led by Professors Keary Engle of the Scripps Research Institute and Peng Liu of the University of Pittsburgh. The project focuses on developing new chemical reactions using earth-abundant nickel catalysts to efficiently synthesize valuable compounds, including medicinally relevant molecules, agrochemicals, and functional...
Through a $497,704 Project Grant award from the National Science Foundation's Chemical Catalysis program (CFDA 47.049 Mathematical and Physical Sciences), Professor Ming-Yu Ngai of Purdue University is conducting research to develop new sustainable catalytic processes leveraging first-row transition metals. The project aims to expand understanding of radical migration mechanisms and enable site- and stereoselective functionalization of carbohydrates and other small molecule building blocks....