Project Grant 2143622

Award Date 6/15/22
Completion Date 5/31/27
Dollars Obligated $906K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Albany, CA 94710, USA
Similar Awards
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $448,818 to The Regents of the University of California, Berkeley (UC Berkeley) to develop a miniaturized, sensitive, and user-friendly electromagnetic (EM) sensing platform for rapid bacterial diagnostics. The project aims to combine physics-based dielectric spectroscopy and biochemistry-based magnetic nanoparticle detection to distinguish unique bacterial phenotypes and surface...
This $430,785 National Science Foundation (NSF) CAREER award to the Regents of the University of California at Riverside (UC Riverside), awarded under the NSF Engineering program (CFDA 47.041), is focused on developing novel CRISPR-based biosensing technologies for the ultra-accurate detection of disease-related single nucleotide polymorphisms (SNPs). The central goals of the 5-year project are to: 1) enable ultra-accurate SNP detection using a CRISPR-Cas14 biosensor, 2) design a ratiometric SNP...
This National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070) award of $1,200,000 provides funding to the University of California, Berkeley from October 1, 2024 to September 30, 2028 to develop innovative sensing technologies that integrate DNA nanotechnology and CMOS electronics for next-generation diagnostics. The key objectives of this project grant are to: (1) develop molecular engineering techniques using DNA origami...
The University of California, Berkeley received a three-year $241,592 Project Grant from the National Science Foundation to conduct research titled "Collaborative Research: Engineering MS2 Capsid Assembly Using Systematic Fitness Landscapes." The grant is part of NSF's Engineering program (CFDA 47.041), which aims to improve quality of life and economic strength through engineering innovation and excellence. Under the award, UC Berkeley researchers will work to engineer MS2...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 aims to develop a platform for detecting genetic antibiotic resistance motifs that can predict current and future susceptibility to therapeutics. The project will establish the feasibility of leveraging mutational signatures in bacterial DNA to identify antibiotic resistance status, including the potential for rapid development of multi-drug resistance. This approach...
The National Science Foundation (NSF) awarded a $800,000 Project Grant under its Biological Sciences program (CFDA 47.074) to The Regents of the University of California, doing business as University of California, Berkeley. The grant funding will support collaborative research to discover and characterize compact CRISPR gene editing systems that can be encoded in plant viruses. This will enable more efficient and widespread deployment of genome editing capabilities across a variety of crop...
The Regents of the University of California, doing business as the University of California, Berkeley, received a $600,000 Project Grant award from the National Science Foundation to conduct research under the Biological Sciences program. The goal of the grant is to advance understanding of major biological problems through basic research projects such as TRTECH-PGR: NSF BSF - Recombining Allelic Diversity via Genome Editing for Dissecting Complex Plant Traits. This project will utilize genome...
This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
The National Science Foundation (NSF) awarded a $919,999 Project Grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This 3-year grant, beginning September 1, 2023, supports research to investigate the evolution and functional role of small regulatory RNAs (sRNAs) in diverse bacterial lineages, particularly those living symbiotically within pest insect hosts. The project aims to determine how sRNA sequence divergence and...
The Regents of the University of California, doing business as University of California, Berkeley, received a $545,430 Project Grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation to develop a new nanofabrication approach based on self-assembly of nanoscale materials guided by DNA molecules. This Faculty Early Career Development award, made on May 1, 2023 under the Engineering (47.041) federal grant program, will support research through...

The National Science Foundation awarded $905,966 under the Engineering (47.041) federal grant program to The Regents of the University of California, Berkeley from June 15, 2022 to May 31, 2027.

The award will support the development and validation of a targeted long-read DNA sequencing approach to enable enrichment of antibiotic resistance genes and flanking regions from metagenomic samples. This is intended to facilitate detection of low-abundance antibiotic resistance gene targets and their genomic contexts, such as bacterial hosts or plasmid carriers. The principal investigator plans to combine CRISPR-based enrichment with portable long-read sequencing to build the foundation for more efficient and cost-effective global surveillance platforms that can monitor the spread of antibiotic resistance. Additionally, the award will support educational activities including an undergraduate research module employing portable DNA sequencing technologies to detect clinically relevant antibiotic resistance genes in student-collected soil samples.

Generated 1/6/24, 4:06 PM