Project Grant 2135169
- This Project Grant award of $434,472.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by Claremont McKenna College to develop novel computational methods for inferring microbial associations from microbiome data. The project aims to address challenges in determining the underlying covariance structure and modeling positive and negative interactions between microbial taxa. The resulting computational tools and algorithms will enable new...
- This federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) in the amount of $300,000 supports research by Duke University to develop an integrated experimental and computational approach to uncover the design principles governing microbiome function. The key objectives are to apply advanced machine learning techniques, high-throughput microbial community construction, and metabolomics to elucidate the molecular networks and cellular...
- The National Science Foundation (NSF), under its Biological Sciences program (CFDA 47.074), awarded the University of Wisconsin System $621,502 on August 15, 2023 for a project titled "COLLABORATIVE RESEARCH: EDGE FGT: DEVELOPMENT OF A COMPREHENSIVE SELECTION LIBRARY TO RECONCILE CORE METABOLIC KNOWLEDGE GAPS". The project aims to develop tools and resources (algorithms, strains, and plasmids) to rapidly identify the functions of genes in non-model organisms, in order to better...
- Federal Grant Award Summary The National Science Foundation's Division of Ocean Sciences awarded a $350,000 Project Grant (CFDA 47.050, Geosciences Program) to Bigelow Laboratory for Ocean Sciences effective September 1, 2025, through August 31, 2028. The award supports fundamental research investigating the life-history patterns, systematics, and biogeography of Patescibacteria and Chloroflexota—abundant yet understudied bacterial lineages residing in marine sediments. The primary...
- The National Science Foundation (NSF) awarded a $299,968 EAGER (Early-concept Grants for Exploratory Research) grant to Portland State University (PSU) for the project "Fertilizing the Tree of Life with Novel Taxa from Deep-Sea Vent Microbial Metagenomes Collected Over Time and Space". The grant supports research to characterize the spatial and temporal genomic diversity of microbes found in deep-sea hydrothermal vents across the Atlantic, Pacific, and Indian Oceans. The project will...
- This $763,538 federal Project Grant was awarded to the University of Chicago on July 15, 2024 by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074). The project aims to understand the mechanistic basis of functional robustness in the soil microbiome, connecting detailed microbial processes to broader ecological and environmental outcomes like soil fertility and greenhouse gas emissions. The research objectives include elucidating how soil microbiomes respond to...
- This National Science Foundation Project Grant of $597,248 supports research into applying novel approaches to link microbial growth efficiency, function, and energy transfer in the ocean. Funded under the Geosciences program (CFDA 47.050), the award will further understanding of the integrated Earth system through basic research in ocean sciences. Specifically, the University of Miami Rosenstiel School of Marine and Atmospheric Science will conduct research from September 2023 to August 2026 to...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $299,758 to the University of Washington to develop a novel method for estimating bacterial evolutionary histories. The key products and services to be delivered under this 2-year award include: Implementing and benchmarking a new mathematical approach for averaging gene-level phylogenies to obtain overall phylogenies for bacteria and archaea, even when not all genes are...
- The National Science Foundation (NSF) awarded a $270,000 Postdoctoral Research Fellowship in Biology (PRFB) grant under the Biological Sciences (CFDA 47.074) program. The 3-year grant, which begins on March 1, 2026, will fund research to elucidate the chemical potential of the small intestinal microbiome. The project aims to characterize how individual small intestine microbes and microbial communities respond to host factors and protect against pathogens, with the goal of advancing basic...
- Federal Project Grant Summary Oregon State University received a $150,000 Project Grant award from the National Science Foundation's Division of Mathematical Sciences (CFDA 47.049) effective August 15, 2025, with completion targeted for July 31, 2028. The grant funds the development of flexible and scalable cluster analysis methods designed to identify functional groups of microbes through longitudinal microbiome data analysis. The primary deliverables include the creation and distribution of...
This three-year, $387,240 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support improvements to FAPROTAX, a popular database and computational tool for predicting the metabolic functions encoded by prokaryotic taxa in microbiome surveys. FAPROTAX2 will incorporate additional experimental evidence from literature, redefine metabolic functions consistently with the Metacyc pathway database, include phenotypic data from thousands of prokaryotic genomes, and provide flexibility in balancing prediction sensitivity versus specificity. These enhancements will expand FAPROTAX's applicability and allow for rapid insight into microbial community functional potential without metagenomic sequencing or culturing. Delivered through the University of Oregon, FAPROTAX2 will be the only tool enabling broad phenotypic predictions in marker-gene microbiome surveys based on both experimental and genomic evidence, benefiting research on environmental, industrial, agricultural, and human health issues involving the microbiota.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $387.2k | 1/21/22 |