Project Grant 2133725
- This three-year, $525,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports coordinated mechanistic approaches to desulfonation in two-component FMN monooxygenases. East Carolina University will deliver structural investigations of alkane sulfonate monooxygenase systems through X-ray crystallography and analysis, with the University of Massachusetts Boston performing the crystallography work. Quantum mechanical calculations...
- This $525,000 Project Grant awarded by the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), will fund research by Professor Holly Ellis and her team at East Carolina University to study the functional and structural properties of a recently identified enzyme system involved in persulfide oxidation. The project focuses on elucidating the catalytic mechanism and structural features of the mercaptopropionate...
- East Carolina University was awarded a $134,447 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) to support research titled "C*-ENVELOPES AND OTHER THEMES IN OPERATOR ALGEBRAS" from July 15, 2021 through June 30, 2024. Under this award, the university will conduct research into operator algebras and their applications in mathematics, with a focus on C*-envelopes and related topics. The NSF's Mathematical and Physical Sciences...
- This Project Grant award for $450,000 was provided by the National Science Foundation (NSF) through the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The funding supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University to investigate a group of four enzymes that utilize a single iron atom and molecular oxygen to catalyze diverse chemical reactions. The goal is to elucidate the...
- This Project Grant award, valued at $785,000.00 and funded by the Chemical Mechanism, Function, and Properties Program (CFDA# 47.049) of the National Science Foundation's Division of Chemistry, supports Professor Pier Alexandre Champagne of the New Jersey Institute of Technology in advancing the chemical understanding of reactive sulfur species. The project employs a combination of experimental and computational techniques to develop new synthetic donors of reactive sulfur species, use these...
- This Project Grant award, valued at $450,000.00, was provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program. The award, effective from August 1, 2024 to July 31, 2027, supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University. The objective of this research program is to elucidate the fundamental mechanisms by which a...
- The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $234,925 Project Grant to the University of Florida. The funding supports research conducted by Professor Kate Carroll to investigate post-translational protein cysteine modifications and the chemical reactivity of sulfur. The research explores how different cysteine thiol group modifications impact the properties of the sulfur atom, which is essential for understanding the role...
- The National Science Foundation (NSF) Division of Chemistry awarded a $550,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of North Carolina at Chapel Hill (UNC-CH) for a 3-year project. The objective is to establish light-activated reactions that form transition metal hydride complexes, which are critical for producing fuels and commodity chemicals. The research activities will study the electronic structure and photochemistry of...
- The University of California, Santa Barbara will receive $500,000 from the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) from September 1, 2021 to August 31, 2024. The funding will support the project "Harnessing the Reactivity of Sulfur: From Novel S-Atom Transfer Reagents to Sulfide-Protected Nanoclusters," which aims to advance the understanding of sulfur chemistry through development of new sulfur-transfer...
- The University of Pittsburgh received a $506,906 Project Grant award from the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support fundamental mechanistic studies of oxidative carbon-hydrogen bond cleavage processes and their application to new chemical reaction design. Professor Paul Floreancig and his research team will investigate remote functional group effects on hydride abstraction kinetics using...
East Carolina University received a $140,677 Project Grant award from the National Science Foundation Division of Chemistry on June 1, 2021 to support research titled "Mechanistic and Structural Approaches for Sulfur Acquisition in the Two-Component FMN-Dependent Monooxygenases" through January 31, 2022. The award was made under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise through increasing knowledge and enhancing understanding of major problems. Specifically, the funding supported East Carolina University's research into the mechanistic and structural processes by which certain enzymes acquire sulfur during chemical reactions involving flavin mononucleotide, in order to advance foundational knowledge in chemistry.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $140.7k | 6/3/21 |