This $270,241 federal Project Grant award, provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports research conducted by Trustees of Dartmouth College to characterize evolutionarily conserved plant signaling modules that underlie organ development. The 5-year project, running from June 2025 through May 2030, will utilize the non-seed plant model Physcomitrium patens and genome editing techniques to map signaling pathways from novel peptides to...
This National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant awarded $479,855 to Trustees of Dartmouth College to conduct research aimed at expanding the substrate range of the cellulolytic microbe Clostridium thermocellum. The goal is to improve understanding of C. thermocellum's metabolism and identify factors limiting its ability to deconstruct lignocellulosic biomass, a major renewable feedstock for biofuels and bioproducts. The project involves characterizing...
This National Science Foundation (NSF) Project Grant under the Biological Sciences program (CFDA 47.074) will fund research at Dartmouth College to investigate how plants integrate signals related to iron availability and light conditions. The $809,225 award made on March 1, 2024 will support experiments to understand the role of the URI protein in regulating iron uptake and utilization by plants. The research aims to improve understanding of how plants coordinate their responses to iron...
The National Science Foundation awarded a $361,777 Project Grant to the University of Georgia under the Biological Sciences program (CFDA 47.074) to conduct research on the hormonal regulation of cellulose synthase complexes in plants. The project aims to elucidate how plants control the synthesis of cellulose, a critical polysaccharide for plant growth, through post-translational phosphorylation of cellulose synthase enzymes. The research will employ advanced genetic, biochemical, and cell...
Trustees of Dartmouth College will receive $269,822 from the National Science Foundation under the Geosciences program (CFDA 47.050) to conduct collaborative research on eukaryotic life and its preservation within the Mesoproterozoic Lower Belt Supergroup. Dartmouth researchers will combine lithostratigraphy, magnetostratigraphy, and detrital geochronological analysis of fossil-rich formations in Montana to better understand early eukaryote evolution and diversification patterns. The project...
The National Science Foundation awarded Dartmouth College $520,267 under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) from July 1, 2023 to June 30, 2026. Dartmouth will conduct research on hydrazone-based feedback loops to study how molecular switches can communicate and be used to control ensembles of molecules. This work aims to further fundamental understanding of engineering reaction cascades and self-assembling systems that can autonomously regulate catalysis...
This $337,667 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program will support research to enhance an inducible protein degradation tool called E3-DART for use in plant cell biology. The goals are to develop a ligand-inducible version of E3-DART, create additional recombinant tools to control its activity, and demonstrate its capabilities for studying endomembrane protein function and synchronized secretory protein trafficking in...
This federal Project Grant award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) provides $373,450 to Michigan State University from September 1, 2023 to August 31, 2026 to conduct research on understanding the cellulose synthase complex in living plants using advanced microscopy techniques. The research aims to visualize in real-time the enzymes responsible for cellulose biosynthesis at the subcellular and...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $293,514 Project Grant to The Trustees of Trinity College in Hartford, Connecticut. The grant supports research from September 1, 2021 to August 31, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds development of microelectrophoretic and statistical tools to study kinase- and reactive oxygen species-based signaling pathways in the social amoeba Dictyostelium discoideum. The...
Cornell University was awarded a $476,779 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant falls under the Biological Sciences program (CFDA 47.074) to support collaborative research titled "Mechanisms of Differentiation and Morphogenesis of the Ligule/Auricle Hinge." The research will be conducted from August 1, 2021 through July 31, 2024 in Ithaca, NY. The Biological Sciences program aims to increase scientific knowledge and...