Project Grant 2123243
- The National Science Foundation awarded a $514,999 Project Grant to the President and Fellows of Harvard College from February 15, 2021 through January 31, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research to design a minimized genome cyanobacterial chassis for efficient bioproduction. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through increasing...
- The National Science Foundation awarded a $759,295 Project Grant to President and Fellows of Harvard College, doing business as Harvard University, to support research titled "TRANSITIONS: SPATIOTEMPORAL BEHAVIORS OF METABOLIC FLUXES IN CELL BIOLOGY." The funding period is from January 15, 2021 through December 31, 2023. The grant is being administered under the NSF's Biological Sciences program (CFDA 47.074), which aims to increase scientific knowledge and understanding of major...
- This $1,120,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) aims to explore the boundaries of life's genetic alphabet beyond the natural 4-letter system (A, T, G, C). The research will develop model systems to study the biomolecular properties of a 6-letter genetic alphabet (A, T, G, C, P, Z) and map critical interactions necessary for translation of this expanded genetic code. The project will use synthetic biology and chemical...
- The National Science Foundation awarded a $186,224 Project Grant to the President and Fellows of Harvard College from the Engineering program (CFDA 47.041) for work on "COLLABORATIVE RESEARCH: DROPLET-BASED SELECTION TO IMPROVE AFLATOXIN DETOXIFICATION." This three-year award, made on August 1, 2021 and running through July 31, 2024, will support research into using droplet-based selection methods to improve aflatoxin detoxification. The Engineering program seeks to foster innovation...
- The Foundation For Applied Molecular Evolution, Inc. was awarded a $1.2 million Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences to support research titled "COLLABORATIVE RESEARCH: SYNTHETIC AND SYSTEMS BIOLOGY APPROACHES TO SEMI-SYNTHETIC CELLS WITH EXPANDED DNA ALPHABETS" from August 15, 2021 through July 31, 2024. The grant supports research under the NSF's Biological Sciences program (CFDA 47.074), which aims to advance fundamental...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,299,732 to the University of Texas at Austin under a Project Grant to support research titled "COLLABORATIVE RESEARCH: SYNTHETIC AND SYSTEMS BIOLOGY APPROACHES TO SEMI-SYNTHETIC CELLS WITH EXPANDED DNA ALPHABETS." The three-year award beginning August 15, 2021 falls under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and strengthen the Nation's...
- The National Science Foundation Division of Integrative Organismal Systems awarded a $314,715 Project Grant to President And Fellows Of Harvard College from September 1, 2021 to August 31, 2024. The grant supports collaborative research titled "EDGE FGT: Transformation and Genomic Resources to Advance Diverse, Emerging Model Angiosperms" under the Biological Sciences program (CFDA 47.074). The research aims to promote progress in the biological sciences by increasing scientific...
- This $1,373,044 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the Massachusetts Institute of Technology to develop microbial strains with minimal genomes for integrated bioprocessing using supercritical carbon dioxide. The goal is to elucidate the genotype-phenotype relationship of tolerance to supercritical CO2 for a selected microorganism and construct a reduced genome strain displaying the desired tolerance phenotype....
- The National Science Foundation awarded a $367,636 Project Grant to the Massachusetts Institute of Technology from March 1, 2021 through February 29, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research on multidimensional single-cell phenotyping to elucidate relationships between genomes and phenotypes. The Biological Sciences program aims to advance biological knowledge and understanding of major problems through basic research. This award supports...
- The National Science Foundation awarded a $138,000 Project Grant to support research titled "Understanding Protein Synthesis in Energetically Constrained Microbial Consortia" from September 1, 2021 through August 31, 2023. The grant was awarded under the Biological Sciences program (CFDA 47.074) to further the program's goals of advancing the biological sciences and strengthening the scientific enterprise through increased knowledge and understanding of major issues facing the...
This three-year Project Grant from the National Science Foundation, totaling $1,996,695, will support research to expand the functions of a 57 codon recoded E. coli genome. The award was made on August 1, 2021 to President and Fellows of Harvard College, with performance taking place in Cambridge, Massachusetts. The research aims to promote progress in the biological sciences by increasing scientific knowledge and enhancing understanding of major problems, as outlined in the Biological Sciences program (CFDA 47.074) of the NSF. Specifically, the funding will allow the grantee to further develop a recoded E. coli genome with a reduced codon set, with the goal of better understanding the genome's functionality and ability to support new biosynthetic pathways. Insights gained from this work have the potential to advance synthetic biology and biomanufacturing applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.0m | 7/29/21 |