Project Grant 2109051
- The National Science Foundation Division of Chemistry awarded a $494,550 Project Grant to the University of Georgia Research Foundation to support research investigating new protein post-translational modifications derived from valine metabolism. Under the Mathematical and Physical Sciences federal grant program (CFDA 47.049), principal investigator Y. George Zheng and early career trainees will identify and validate two novel post-translational modifications, lysine methacrylylation and...
- This $525,000 Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will fund research at New York University from June 2022 to May 2025 to develop synthetic analogs of the small protein ubiquitin using block copolymers. Professor Marcus Weck will employ innovative design principles to fold and assemble artificial versions of ubiquitin through the use of folding synthetic polymers with protein-like...
- The National Science Foundation awarded a $698,430 project grant to the Georgia State University Research Foundation Inc. from August 1, 2021 to July 31, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The grant funds research to shed light on the photochemistry of the LOV class of flavin photoreceptors. As part of the Mathematical and Physical Sciences program's goals to promote progress in the mathematical and physical sciences and strengthen the nation's scientific...
- This $440,262 federal Project Grant award was provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) grant program. The award supports a collaborative research project between professors at the Georgia Institute of Technology and Utah State University to study the evolution of archaeal protein tyrosine phosphatases (PTPs), a family of enzymes crucial for cellular signaling processes. The research aims to quantitatively...
- The University of Kentucky Research Foundation was awarded a $780,000 Project Grant from the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop new chemical tools to study protein function through metal-mediated ligand affinity chemistry. Principal Investigator Samuel G. Awuah and his research team will apply synthetic chemistry and molecular biology approaches to study reactions of specific amino acids...
- This $597,945 federal Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program supports research by Tobias W. Giessen at the University of Michigan, Ann Arbor to investigate the structure and function of peptide-modifying enzyme filaments found in bacteria and archaea. The proposed work will generate new insights into the self-assembly and catalytic activity of these filamentous enzymes, which...
- This $414,390 National Science Foundation project grant supports research at Eastern Michigan University to advance understanding of autophagy, a cellular recycling and protection process. Funded under the NSF Biological Sciences program (CFDA 47.074), the three-year award beginning in February 2023 will investigate the molecular mechanisms that drive formation of the autophagosome, a vesicle that degrades cellular cargo. Researchers will study proteins involved in conjugating the ATG8 protein...
- This $574,915 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) supports research by Professor Monika Raj of Emory University to develop new chemical probes and strategies for detecting and studying modifications to the amino acid histidine in proteins. The goal is to create novel chemical probes capable of selectively labeling modified histidine residues in proteins and capturing the...
- The National Science Foundation Division of Chemistry awarded a $450,000 Project Grant to the Georgia Tech Research Corporation from January 1, 2022 to December 31, 2024 under the Mathematical and Physical Sciences program (CFDA 47.049). The grant funds research into noble-metal nanocrystals in metastable phases, with a sub-award to the University of Wisconsin-Madison for contributions in understanding the fundamental physics and chemistry underlying growth of metastable phases of metal...
- This Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $480,000 to Professor Michel R. Gagné of the University of North Carolina at Chapel Hill from August 1, 2022 to July 31, 2025. The funding supports research into new catalytic processes using unsupported z-ligands as key initiators. Specifically, the Gagné group will study the fundamental reactivity and potential structural variability of...
The National Science Foundation Division of Chemistry awarded a $729,999 Project Grant to Georgia State University Research Foundation Inc. under the Mathematical and Physical Sciences program (CFDA 47.049) for work on "ELUCIDATING THE ROLES OF E3 LIGASES AND DEUBIQUITINATING ENZYMES IN MITOPHAGY BY ORTHOGONAL UBIQUITIN TRANSFER AND LINKAGE-SPECIFIC UBIQUITIN PROBES" from August 1, 2021 to July 31, 2024. The University will research the roles of E3 ligases and deubiquitinating enzymes in mitophagy through development of orthogonal ubiquitin transfer techniques and linkage-specific ubiquitin probes. A $100,000 subaward was also provided to Virginia Commonwealth University to produce and purify ubiquitin variants containing unnatural amino acids for use in chain and inhibitor synthesis, and to develop technologies enabling incorporation of required amino acids.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $52.0k | 8/5/22 | ||
| Not listed | $678.0k | 5/18/21 |
GrantNumber | Description | Subgrantee | Prime Award | Dollars Obligated | Updated At |
|---|---|---|---|---|---|
SP0001490501S | Virginia Commonwealth University | Project Grant 2109051 | $165.0k | 1/17/24 |