The University of California, San Diego will deliver a project titled "Responsive Materials from Self-Assembling Nucleic Acid Nanoshapes" through a $535,012 Project Grant from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049). The three-year award running from July 2021 to June 2024 will support research into developing responsive materials using self-assembling nucleic acid nanostructures. The Mathematical and Physical Sciences program aims to advance scientific knowledge and enhance understanding of major problems through support of mathematical and physical sciences research and education activities. As the sole awardee, UC San Diego will leverage the funding to explore creating materials with programmable responses to external stimuli through precise control of nucleic acid nanoshapes at the molecular level.