The University of California, San Diego will receive $1.5 million over five years from the National Science Foundation under its Biological Sciences program (CFDA 47.074) to conduct a project titled "CHEMOENZYMATIC CONSTRUCTION OF A PROGRAMMABLE SYNTHETIC ENDOPLASMIC RETICULUM." From August 2021 through July 2026, UCSD researchers will work to develop new techniques for engineering the endoplasmic reticulum, a cellular organelle, using enzymatic and chemical methods. The Biological...
The National Science Foundation awarded $670,036 to the University of California, San Diego under Project Grant number 47.041, the Engineering program, to support the project "ELUCIDATING ESSENTIAL FACTORS FOR PRODUCTION OF RECOMBINANT SECRETED PROTEINS THROUGH PROTEOMICS" from April 1, 2021 through March 31, 2024. The University of California, San Diego will utilize the funding to elucidate essential factors for the production of recombinant secreted proteins through proteomics. As...
The University of California, San Diego received a $300,000 Project Grant award from the National Science Foundation on February 1, 2021 to develop a high-throughput in vivo method for measuring transcription factor-DNA interactions. The grant supports research under the NSF's Biological Sciences program (CFDA 47.074) through January 31, 2023. The Biological Sciences program aims to advance the fundamental biological sciences and enhance understanding of major problems through basic research....
The National Science Foundation awarded a $538,838 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to The Regents of the University of California, San Francisco for research titled "Collaborative Research: Mapping Protein-Membrane Interactions from Molecules to Cell-Level Dynamics." The research will develop multiscale models to map how individual protein structures and compositions interact with and deform cell membranes at varying scales, from...
This National Science Foundation Project Grant of $536,946 will support research at the University of California, San Diego from September 2022 through August 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). The award will fund the development of rigorous scientific theories and powerful computational tools to model biomolecular interactions. Researchers will design advanced numerical methods to simulate drug and protein binding/unbinding kinetics, incorporating molecular...
This Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences provides $300,000 to the University of California, San Diego for research titled "EAGER: DEVELOPING A HIGHLY SELECTIVE, ORTHOGONAL, ENZYMATIC RNA LABELING TECHNOLOGY VIA DIRECTED EVOLUTION OF AN RNA TRANSGLYCOSYLASE." The period of performance is from August 15, 2021 to July 31, 2023. The funding supports research under the NSF's Biological Sciences program (CFDA 47.074). The goal...
The Regents of the University of California, doing business as the University of California, Berkeley, received a $950,013 Project Grant award from the National Science Foundation on January 15, 2021 to fund research understanding the protein composition and dynamics of the nuclear envelope in plants. The research is being conducted under the NSF's Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific...
This $1.4 million project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the California Institute of Technology from July 2022 to June 2026 to understand the regulation and fidelity of the signal recognition particle (SRP) in eukaryotic cells. SRP is a universally conserved protein targeting system that ensures newly synthesized proteins are delivered to the correct cellular locations. The grantees will investigate how SRP is regulated...
The University of California, San Diego will deliver a project titled "Responsive Materials from Self-Assembling Nucleic Acid Nanoshapes" through a $535,012 Project Grant from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049). The three-year award running from July 2021 to June 2024 will support research into developing responsive materials using self-assembling nucleic acid nanostructures. The Mathematical and Physical Sciences...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $738,612 Project Grant to the University of Delaware under the Biological Sciences federal grant program (CFDA 47.074) for the period of August 1, 2021 through July 31, 2025. The grant funds research into membrane fluidity and its fundamental and functional roles. The University of Delaware will conduct theoretical and computational research, while the University of California San Diego will receive a...