Project Grant 20266701645731
- This $650,000 Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program will support research on the role of interleukin-6 (IL6) family signaling proteins in early embryo and placental development in cattle. The 4-year project, running from Feb 1, 2026 to Jan 31, 2030, aims to: 1) Determine how IL6-family signals help an early embryo form properly, 2) Understand how...
- The Texas A&M AgriLife Research project, funded by a $225,000 Agriculture and Food Research Initiative (AFRI) grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture (CFDA 10.310), will investigate how pregnancy and pregnancy-associated glycoproteins (PAGs) secreted by the bovine placenta modulate maternal immune responsiveness, promoting tolerance of the embryo and placenta. The study will examine changes in uterine immune cell populations and functions...
- This $300,000 Project Grant awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) aims to identify epigenetic modifications in the cattle placenta that are specifically from the sire or the dam, and determine how they influence gene expression during placental development. The overarching goal is to improve understanding of the complex biology of the placenta and how...
- This $650,000 Project Grant was awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program on July 1, 2024. The grant aims to characterize placental cell types in the maternal endometrium during early stages of development in cattle, using cutting-edge techniques. The long-term goals are to understand how the placenta develops, how it interacts with the uterus, and what cells and molecules are involved in the process. A...
- This Project Grant award of $650,000.00 was provided by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant supports research at Texas A&M AgriLife Research aimed at understanding the biological mechanisms underlying embryonic mortality in cattle. The central hypothesis to be investigated is that male and female genetics contribute differently to pregnancy...
- This $500,000 project grant from the United States Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) supports research under the Agriculture and Food Research Initiative competitive federal grants program (AFRI; CFDA #10.310). The Virginia Polytechnic Institute and State University will characterize differences in early embryonic development and uterine environments between cattle breeds that are more resilient to undernutrition and less prone to pregnancy loss,...
- This $650,000 Project Grant awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (CFDA 10.310) supports research at Utah State University (USU) to characterize the role of placental vesicles in regulating fetal development and maternal immune responses during pregnancy. The central objective is to determine how placental vesicles derived from healthy pregnancies versus abortion-prone pregnancies modulate the maternal uterine...
- This $650,000 Agriculture and Food Research Initiative (AFRI) Project Grant, awarded by the USDA National Institute of Food and Agriculture (CFDA 10.310), aims to improve the reproductive success of high-producing dairy cows. The research project has two main objectives: 1) understanding the nutritional needs of dairy cow embryos, particularly differences between lactating cows and younger heifers, in order to identify ways to better support embryo development; and 2) examining how oxygen and...
- This $225,000 federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) CFDA 10.310 program supports research to improve in vitro embryo production (IVP) techniques for cattle. The project aims to determine if supplementing or inhibiting the action of "embryokines" - biological factors found in the uterus and embryo that are essential for embryo development and...
- This $300,000 federal Project Grant award was provided by the USDA National Institute of Food and Agriculture (NIFA) through the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The project aims to evaluate the long-term impacts of strategic supplementation and nutritional restriction during gestation on the development and reproductive capacity of ewe lambs at Colorado State University. Key objectives are to determine how maternal nutrition impacts ewe lamb puberty,...
This $300,000 project grant was awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The objective is to determine the functional role of the progesterone receptor membrane component 1 (PGRMC1) in regulating peri-implantation conceptus survival, development, placental formation, and pregnancy establishment in cattle. The research aims to: (1) evaluate the effects of embryonic PGRMC1 ablation on peri-implantation conceptus survival and development, and (2) assess the impacts of embryonic PGRMC1 ablation on placental development and pregnancy establishment and survival. The project will be conducted at the University of Wyoming from February 2026 to January 2028. This research seeks to advance the fundamental understanding of how PGRMC1 regulates early pregnancy success in cattle, which could lead to future efforts to improve reproductive efficiency in cattle production systems.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.0k | 12/30/25 |