This Project Grant award of $225,000 was provided by the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program. The funding will support research conducted by Texas A&M AgriLife Research to investigate how pregnancy and pregnancy-associated glycoproteins (PAGs) secreted by the placenta modulate maternal immune responsiveness, promoting tolerance of the embryo and placenta in cattle. The objectives are to: 1) examine changes in uterine immune cell populations and functions during placental attachment, and 2) determine if PAGs can alter the immune response of uterine and ovarian cells. This research aims to establish a baseline of immune cell changes during pregnancy and reveal pathways that may be modified to reduce pregnancy loss, which is estimated to affect 50% of cattle in the first month of pregnancy and contribute significant economic losses. The award period is from Jul 1, 2025 to Jun 30, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $225.0k | 6/30/25 |