The University of Nebraska was awarded a $649,927 Project Grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program. The objective is to develop microbiota-based strategies that protect the host from cadmium (Cd) toxicity. The research will employ human microbiota-associated mice to determine the role of Cd tolerance of the gut microbiota and Cd-tolerant bacteria in mediating Cd accumulation and oxidative stress in host tissues. The project will also identify the protective effect of dietary fiber on the gut microbiota against Cd toxicity. This research addresses the priority areas of the AFRI program by investigating the interrelationship among foods, Cd, and the human gut microbiome, and will help shape dietary recommendations to protect the public from Cd toxicity. The award period is from June 1, 2024 to May 31, 2027.
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