Project Grant 20236701540731
- The University of Illinois was awarded a $650,000 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) federal grant program. The four-year grant will fund research to develop an improved vaccine candidate for Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a significant pathogen affecting the U.S. pork industry. Key areas of focus include removing viral interferon...
- The Department of Agriculture's National Institute of Food and Agriculture awarded a $635,000 Project Grant to the University of Illinois under the Agriculture and Food Research Initiative competitive grants program. The three-year award will fund research to develop diagnostic assays and strategies to better surveil and prevent Porcine Reproductive and Respiratory Syndrome Virus, a significant pathogen affecting the U.S. swine industry. Specifically, the University of Illinois will dissect...
- This Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) CFDA 10.310 program provides $649,991 to the University of Illinois to conduct research on inflammatory responses in swine. The project aims to compare gene expression profiles in macrophages from wild-type and CD163 knockout pigs, evaluate the impact of porcine circovirus type 2D infection on macrophage inflammatory...
- The University of Nebraska was awarded a $627,000 Project Grant from the US Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The three-year award running from May 1, 2023 to April 30, 2026 will support research on porcine reproductive and respiratory syndrome virus (PRRSV) infection pathways and identification of additional cellular factors required for PRRSV replication. Specifically, the...
- The University of Illinois received a $800,000 three-year Project Grant award from the United States Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The University will evaluate the protective efficacy of Orf virus and Pseudorabies virus vectors expressing African Swine Fever Virus protective antigens of the epidemic Georgia-07 strain through vaccination challenge experiments in pigs. It will...
- The University of Illinois has received a $650,000 Project Grant award from the U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program. The goal of this 3-year project is to develop a cell-free Marek's disease vaccine that can provide better protection for chickens without the added cost of liquid nitrogen storage required for current cell-associated Marek's disease vaccines. The researchers aim to...
- The Regents of the University of Minnesota received a $799,993 Project Grant award from the United States Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) federal grant program (CFDA #10.310). The grant will fund the creation of an integrative data science platform to predict the immunogenic and epidemiologic phenotype of Porcine Reproductive and Respiratory Syndrome Virus-Type 2 (PRRSV-2) variants through applying...
- The USDA National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to Louisiana State University (LSU) to engineer a novel vaccine vector platform. The key objectives are to: Incorporate PRRSV envelope proteins into a pseudorabies virus vector and evaluate its protective efficacy against virulent PRRSV challenge strains. PRRSV is a devastating swine virus that causes significant economic losses in the...
- This federal Project Grant award of $237,204.00 from the USDA's National Institute of Food and Agriculture (NIFA), under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), will fund research into using gut microbiome modulation as an alternative approach to control Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in swine. The key objectives of this 18-month project, led by the Regents of the University of Minnesota, are to investigate the effects of microbiome...
- This $225,000 USDA Agriculture and Food Research Initiative (AFRI) Project Grant awarded to Virginia Tech on September 1, 2024 supports research on mitigating the impacts of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in pigs through nutritional interventions. The project aims to characterize the metabolic and macronutrient consumption changes in PRRSV-infected pigs when provided amino acids potentially important for the immune response and animal growth. By placing intravenous...
The University of Illinois has received a $650,000 Project Grant award from the U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program. The purpose of this 4-year grant is to conduct research to identify specific regions and domains in the CD163 protein that are critical for infection by the porcine reproductive and respiratory syndrome virus (PRRSV). The research aims to generate modifications to the CD163 receptor that could prevent PRRSV infection without affecting the receptor's key biological functions. The findings are expected to provide critical information for developing novel strategies to prevent or block PRRSV infection, such as new vaccines and small molecules that can disrupt the virus-CD163 interaction.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.0k | 7/19/23 |