Project Grant 20236701140390
- The University of California, Riverside received a $180,000 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The three-year award will support research examining the genetic regulatory networks controlling the development of suberized transport barriers in rice root cells, which show plasticity in response to water stress. Understanding these networks...
- This $249,000 National Science Foundation project grant funds the development of computational and experimental tools to engineer gene expression in rice. Funded under the Biological Sciences program (CFDA 47.074), the award supports a postdoctoral fellowship held by David Ding at the University of California, Berkeley from July 1, 2023 to June 30, 2026. The fellow will create a pipeline to understand regulatory mutations in plants at scale, coupled with high-throughput experimental assays. A...
- The Cornell University Office of Sponsored Programs received a three-year, $648,068 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) competitive grants program (CFDA #10.310). The grant will fund research to gain a further understanding of chilling tolerance mechanisms in crop plants through the study of a rice casein kinase gene (CTK1) and its natural variants in both rice...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $503,000 Project Grant to the University of Texas Rio Grande Valley (UTRGV) under the Biological Sciences program (CFDA 47.074) to study the roles of RNA modifications in regulating responses to abiotic stresses like drought and heat in cereal crops. The project aims to identify novel regulatory mechanisms and new targets for improving drought and heat tolerance in crops like sorghum, maize, rice,...
- This National Science Foundation Project Grant of $921,054 supports research to develop new biological functions through engineering plant hormone receptors. Led by the Regents of the University of California, Riverside under the Biological Sciences program (CFDA 47.074), the project engineers plant sensors to recognize pharmaceuticals and dietary molecules. It then uses these sensors to design "sentinel cells" that indicate molecule presence through color changes. Specifically, the...
- Federal Grant Award Summary The National Science Foundation's Division of Integrative Organismal Systems awarded $613,292 under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside for the TRILATERAL FPP 2023 project titled "FLORESENG - Engineering Endogenous Oxygen Sensing for Improved Flood Resilience in Cereals." The three-year project, effective from July 1, 2025 through June 30, 2028, delivers fundamental research aimed at...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) federal Project Grant award to Duke University will support research focused on elucidating the molecular mechanisms underlying the function of DELLA proteins, which are master growth regulators in plants. The $1,337,663 award will fund investigations into how DELLA proteins control gene expression and how their activity is regulated through phosphorylation, with the goal of enhancing strategies to manipulate...
- This three-year Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $1,342,282 to Texas Tech University to conduct collaborative research unraveling the origin of vegetative desiccation tolerance in vascular plants. The research team will seek to identify genes that act as master regulators of desiccation tolerance by comparing the dynamic responses of green tissues and seeds in desiccation-tolerant and sensitive plants. Specifically, the...
- This $299,496 federal Project Grant award from the USDA's Agriculture and Food Research Initiative (AFRI) program, CFDA 10.310, aims to build gene regulatory networks that combine gene expression and epigenomic data from nitrogen and CO2 treatments to enhance the accuracy of predictions and identify key transcription factors involved in coordinating carbon-nitrogen homeostasis in legumes. The goal is to develop strategies to achieve maximum crop yield and quality in future climates. The award...
- This $445,676 National Science Foundation project grant supports research at Rutgers University, Camden investigating the role of the plant hormone abscisic acid in stomatal formation using a drought-tolerant mutant plant. The goal is to gain new insights into how drought controls stomatal numbers to improve plant drought tolerance. Four undergraduate students from underserved communities will conduct much of the research under faculty mentorship. The students will also help develop a new...
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** CELLS CAN COMMUNICATE USING CHEMICAL SIGNALS, OR LIGANDS. WITHIN THE CELL MEMBRANE THERE ARE PROTEIN RECEPTORS THAT BIND THESE LIGANDS. ONCE THE RECEPTOR BINDS THE LIGAND, A SIGNALING CASCADE IS STARTED USING SECONDARY MESSENGERS. ONE CLASS OF THESE SECONDARY MESSENGERS IS HETEROTRIMERIC G PROTEINS WHICH CAN MEDIATE SIGNALING BETWEEN THE CELL SURFACE AND CELL INTERIOR. G PROTEINS CONSIST OF G & ALPHA;, G & BETA;, AND G & GAMMA; SUBUNITS. RICE PLANTS WITH MUTATIONS IN THE G & ALPHA; SUBUNIT, RGA1/D1, HAVE INCREASED DROUGHT RESISTANCE. HOWEVER, THE BIOLOGICAL BASIS FOR THIS IS UNKNOWN. DUE TO CLIMATE CHANGE, DROUGHT IS AN EMERGING PERVASIVE PROBLEM IMPEDING RICE PRODUCTION. IN RICE, MILD DROUGHT CAN REDUCE YIELD BY 17%, AND SEVERE DROUGHT CAN REDUCE YIELD UP TO 65%. THEREFORE, IDENTIFYING THE REGULATION AND ROLE OF RGA1 IN DROUGHT STRESS WILL PROVIDE A BETTER UNDERSTANDING OF THE MECHANISMS INVOLVED IN RICE DROUGHT RESPONSES. A PROMOTER IS ONE REGULATOR OF GENE EXPRESSION, AND CONTAINS SHORT CONSERVED SEQUENCES CALLED CIS-ACTING REGULATORY ELEMENTS (CRES) THAT BIND REGULATORY PROTEINS CALLED TRANSCRIPTION FACTORS. TO STUDY WHICH CRES ARE INVOLVED IN RGA1 GENE EXPRESSION DURING DROUGHT, THE RGA1 PROMOTER WILL BE DIVIDED INTO DIFFERENT SEGMENTS AND CHANGES IN PLANT DEVELOPMENT AND DROUGHT STRESS RESPONSES WILL BE MEASURED. IN ADDITION, THIS RESEARCH WILL UTILIZE A CHEMICAL TAGGING APPROACH TO IDENTIFY WHICH PROTEINS RGA1 INTERACTS WITH DURING DROUGHT. TOGETHER THESE DATA CAN IDENTIFY POSSIBLE TARGETS FOR IMPROVING DROUGHT TOLERANCE IN RICE. IMPROVED DROUGHT TOLERANCE WILL LEAD TO REDUCED YIELD LOSS DURING PERIODS OF DROUGHT, THEREBY PREVENTING ECONOMIC LOSS AND FOOD SHORTAGES.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $180.0k | 5/31/23 |