Project Grant 1937997

The National Human Genome Research Institute (NHGRI) awarded a $1,050,000 Cooperative Agreement under the Human Genome Research program (CFDA 93.172) to the University of North Carolina at Chapel Hill (UNC-CH) to support three biennial conferences of the Ethical, Legal, and Social Implications (ELSI) Research Program between 2026 and 2030. The conferences aim to expand the reach of ELSI research to new generations, communities, and disciplines, and utilize innovative horizon scanning methods...

This $400,000 Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program supports the development of secure methods to enable researchers to analyze their genetic data using controlled-access reference datasets without compromising data privacy. The project, titled "Confidential Genome Imputation and Analytics (COGIA)," aims to create secure algorithms and deployment-ready software for genome analysis in trusted...

This Cooperative Agreement award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $1,310,799 to the University of California, San Diego (UCSD) to develop tools that leverage human reference pangenomes to improve the analysis of complex genetic traits. The key products and services to be delivered include: A web-based pangenome browser that integrates with existing biobank datasets based on linear genomes to enable exploration and visualization of...

This $1,645,076 Cooperative Agreement award from the National Human Genome Research Institute (NHGRI) under the Human Genome Research (CFDA 93.172) program will develop advanced tools and resources to enable new ways to access and understand the human pangenome. The key products and services to be delivered include: Sequence alignment and population genetic analysis methods to rapidly search, compare, and interpret pangenome data, leveraging succinct data structures for scalable pangenome...

This $420,000 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) supports collaborative research by Northeastern University to develop methods for protecting privacy and promoting fairness in advanced genomic research using federated learning approaches. The research aims to enable secure integration of multi-cohort genomic and genetic datasets from different institutions, which is critical for...

This award from the National Science Foundation's Division of Environmental Biology supports a research project at Purdue University to investigate the genetic basis of how organisms adapt to their environment, including the role of non-additive genetic effects. The $198,915 Project Grant, awarded on September 15, 2023, will fund research using a unique set of genetic resources to quantify the contribution of non-additive effects on survival and seed production in the model organism...

This Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on developing a genome editor therapy for Angelman Syndrome, a severe neurodevelopmental disorder. The $1,508,248 award to the University of North Carolina at Chapel Hill will fund a 2-year Discovery (UG3) phase to identify and validate lead AAV-nCas9 vectors that...

This National Science Foundation project grant of $240,000 supports research investigating the genomic consequences of hybridization in the Mimulus guttatus complex from June 2023 through May 2026. Funded under the Biological Sciences program (CFDA 47.074), the award enables a postdoctoral research fellowship for integrative research on the rules governing interactions between genomes, environments and phenotypes during speciation. The fellow will use genomic analyses and greenhouse crosses to...

This three-year Project Grant from the National Science Foundation's Division of Information and Intelligent Systems under the Computer and Information Science and Engineering program ($600,000) will support the development of new computational methods and software for analyzing collections of genomic variants. Specifically, the grantee, Carnegie Mellon University, will create algorithms and open-source software tools to more accurately construct, compare, and assess the complexity of genome...

This $249,000 National Science Foundation Project Grant supports comparative genomics research to understand the genetic regulation of apomixis in the Rosaceae plant family. The award funds a three-year NSF Plant Genome Postdoctoral Research Fellowship for Charity Goeckertiz at the HudsonAlpha Institute for Biotechnology under the supervision of Dr. Alex Harkess. The fellowship supports research and training to compare genomes of Rosaceae species that can and cannot undergo apomixis, the process...