Project Grant 1819562

This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $337,632 to Iowa State University of Science and Technology to develop affordable and accurate tests for detecting bacterial endotoxins. The project aims to create artificial transcription factors that can be used in vitro to detect these harmful substances, which are released from certain bacteria and can cause serious infections and inflammatory responses in...

This SBIR Phase I Project Grant award of $298,646, provided by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a rapid diagnostic test for identifying sepsis-causing pathogens from small blood volumes. The proposed DNA-based technology seeks to comprehensively detect and quantify a wide range of pathogens within a few hours, addressing limitations of current culture-based methods that require larger blood samples and...

The federal Project Grant award from the National Center for Advancing Translational Sciences (NCATS), part of the 93.350 CFDA program, will support the development of a novel biosensor for the detection of bacterial endotoxins. Through this $290,066 award, the awardee Monod Bio, Inc. will focus on (I) computational design and experimental selection of functional lipopolysaccharide (LPS) bioluminescent biosensors, (II) in vitro evolution of these biosensors to optimize sensitivity and stability,...

Coastaloceanvision Inc. was awarded a $300,000 Small Business Innovation Research (SBIR) Project Grant from the National Oceanic and Atmospheric Administration to develop a novel surface enhanced Raman spectroscopy (SERS) technology for rapidly detecting and quantifying human pathogens in seafood. The SERS technology uses a higher energy laser wavelength, an innovative mixture of silver-coated nanoparticles, and a fiber optic probe designed for direct use on seafood tissues and environmental...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop an automated system to streamline the sample preparation process for liquid biopsy cancer testing. The $305,000 award will fund the creation of a microfluidic-based instrument that automates the bisulfite conversion step, a critical but time-consuming and error-prone process in preparing circulating tumor DNA for epigenetic...

This $1,016,000.00 Project Grant award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program will fund the development and application of a low-cost, portable biosensing platform for detecting and monitoring waterborne pathogens in aquaculture and coastal environments. The University of Massachusetts Lowell, as the prime awardee, will lead the effort to adapt its patented biosensing technology to enable real-time pathogen detection and...

This Project Grant from the National Oceanic and Atmospheric Administration's Small Business Innovation Research Program totaling $150,000 will support the development of rapid diagnostic tests for the parasitic infection Amyloodinium ocellatum in fish. Live Advantage Bait, LLC dba Totally Pelagic will utilize next generation approaches to produce highly specific monoclonal antibodies for A. ocellatum dinospores and develop a lateral flow-based rapid diagnostic test. The NOAA SBIR program...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,990 to Scorpido Photonics aims to develop a prototype endoscope-based diagnostic system for rapid, non-invasive detection of microscopic tumors. The project integrates plasmonic nanobubble sensors into a medical device platform and standard endoscope to enable instant, optical detection of cancerous tissues during lung cancer diagnostic procedures. The key product is a...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...