Cooperative Agreement UG3HL175260
- This Cooperative Agreement award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will fund a clinical trial titled "WIN Ratio Analysis to Determine a Strategy of Non-Invasive Support for Respiratory Failure in the Emergency Department (WINDSURFER)". The $688,047 award to the Medical University of South Carolina will support research to determine the best initial non-invasive respiratory support (NIRS) strategy for patients...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $322,277 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Linshom Medical, Inc. in Baltimore, Maryland. The grant will fund clinical development activities focused on demonstrating the health economic value of Linshom's Continuous Predictive Respiratory Monitoring (CPRM) system. The CPRM system aims to reduce morbidity and mortality due to respiratory compromise while lowering healthcare costs...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $816,119 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Oregon Health & Science University (OHSU). The overall objective of this 4-year project is to conduct an in-depth analysis of pediatric prehospital emergency ventilation and identify the ventilation strategy associated with the best patient outcomes. The project will leverage data collected through the NHLBI-funded PEDI-PART trial, which...
- This Project Grant award of $807,067.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will support a study to pioneer the quantitative documentation of human respiratory kinematic profiles. The study aims to address a critical gap in contemporary physiological monitoring - the inability to quantify labored breathing, which contains vital prognostic information not captured by conventional monitoring. Building on a recent innovation called ARK...
- This federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $784,227 to The Ohio State University to engineer an oxygen-carrying perfusate for normothermic machine lung perfusion. The project aims to develop an improved lung perfusion solution to better assess and potentially resuscitate damaged donor lungs for transplantation. This is in response to the critical shortage of viable donor lungs, which has led to the...
- The federal Project Grant award of $678,803.00 was provided by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to The Ohio State University. The funding supports research to investigate the role of the mitochondrial deubiquitinase USP30 in regulating microvascular endothelial cell function and its potential as a therapeutic target for acute inflammatory diseases like acute respiratory distress syndrome (ARDS) and sepsis. Key...
- This federal Project Grant award, totaling $765,612.15, was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research (CFDA 93.837) program. The award supports research to conduct a molecular analysis of airway secretory cells in the context of Chronic Obstructive Pulmonary Disease (COPD), the third leading cause of death in the U.S. and worldwide. The research, taking place at the Research Institute at Nationwide Children's Hospital in Columbus, Ohio,...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), provides $186,408 to the University of Washington to develop robust models that identify patients at high risk for persistent hypoxemic respiratory failure (HRF). The goal is to improve the ability to distinguish patients with persistent HRF early, which is critical for enrolling the highest-risk patients in clinical trials for new HRF...
- The University of Texas Southwestern Medical Center received a $685,724 project grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct a multi-center observational study on the association between ventilation and cardiac arrest outcomes. The study will leverage data from a large clinical trial database to analyze ventilation metrics using a machine learning algorithm developed to measure ventilation during continuous chest...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) totaling $1,480,392 will fund research at Case Western Reserve University (CWRU) to investigate the potential adverse effects of neonatal continuous positive airway pressure (CPAP) on lung development. The research aims to identify mechanisms by which CPAP exposure during the neonatal period can contribute to airway hyperreactivity, wheezing, and other respiratory issues...
The National Heart, Lung, and Blood Institute (NHLBI), through the Cardiovascular Diseases Research program (CFDA 93.837), has awarded a $1,535,439 Cooperative Agreement to The Ohio State University (OSU) for the "WIN Ratio Analysis to Determine a Strategy of Non-Invasive Support for Respiratory Failure in the Emergency Department (WINDSURFER)" project. The project aims to determine the best initial non-invasive respiratory support strategy for treating acute hypoxemic respiratory failure in the emergency department. The funding will support a clinical trial to compare the effectiveness, safety, and patient comfort of two non-invasive respiratory support approaches: non-invasive positive pressure ventilation and heated high-flow nasal oxygen. The award has a start date of September 15, 2025 and a planned completion date of August 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 9/4/25 |