Cooperative Agreement UG3DE035104
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $298,942 Project Grant to Deltamed LLC on August 20, 2025. The grant funding will support the development of a novel "nanosponge prodrug delivery system" for the small molecule MK2 inhibitors apatinib and MMI-0100. The goal is to improve the circulation half-life and targeted delivery of these compounds to mitigate...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $155,500 Project Grant to The University of Iowa. The grant funds a study to identify the causal effects of preventive dental services, including comprehensive oral exams, prophylaxis, fluoride application, and dental sealants, on academic achievement among children enrolled in Medicaid in Iowa. The study aims to determine the ages at...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $304,998 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program to KDH Research & Communication, Inc., a woman-owned small business located in Atlanta, Georgia. Through this grant, KDH Research & Communication will develop a web-based clearinghouse to serve as a centralized hub for researchers and dental providers to increase participation in oral health research and...
- This Cooperative Agreement award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $702,871 to The Washington University in Missouri to conduct research validating a "hybrid epithelial/mesenchymal state" biomarker for predicting treatment response and outcomes in head and neck cancer. The award period runs from August 2025 to May 2030. The key objectives are to: 1) validate an...
- This Project Grant award of $315,000.00 was provided by the National Institute of Dental and Craniofacial Research (NIDCR), which administers the Oral Diseases and Disorders Research federal grant program (CFDA 93.121). The goal of this 2-year project is to study the role of the TRPC1 protein as a potential therapeutic target for treating oral squamous cell carcinoma (OSCC), a common and deadly type of head and neck cancer. The research will focus on understanding how TRPC1 mediates calcium...
- This Project Grant award of $736,507 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) supports the "ONTOLOGY-BASED APPLICATIONS OF MULTI-DISCIPLINARY KNOWLEDGE ON ORODENTAL CONDITIONS AND OUTCOMES (OPULENCE)" research project. The project aims to bridge unmet needs in reporting and conceptualizing orodental sequelae, such as osteoradionecrosis and post-radiation caries, that commonly occur in...
- This Project Grant award of $965,145, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program, aims to examine disparities in oropharyngeal cancer (OPC) outcomes among Medicaid-enrolled adults. The key objectives are to: Characterize differences in early-stage diagnosis and 5-year survival rates for OPCs based on race, ethnicity, sex, and rurality using the SEER-Medicaid dataset. Assess the impact of...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $219,132 Project Grant to Virginia Commonwealth University (VCU) under the Oral Diseases and Disorders Research program (CFDA 93.121). The funding will support a 2-year project titled "Demystifying DMFT/DMFS: Pragmatic Nationwide Assessment of Dental Caries Outcomes from NHANES." The project aims to develop advanced statistical methods for efficiently assessing dental caries experience using complex nationwide...
- This federal Project Grant award in the amount of $469,830.00 was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The grant aims to identify oral bacterial species with anti-cancer properties and evaluate their potential for preventing or treating oral squamous cell carcinoma (OSCC). Specifically, the study will assess the effects of Streptococcus mitis and Haemophilus parainfluenzae on OSCC...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $390,000 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Medical College of Wisconsin, Inc. The grant funds a 5-year research project to leverage single-cell co-culture and gene expression profiling to identify tumor antigen-specific T cells in oral squamous cell carcinoma (OSCC). The project aims to develop innovative methods to isolate and characterize tumor-infiltrating...
This $681,331 Cooperative Agreement award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, supports a clinical trial to test the effectiveness of an intensive preventive dental program administered in oncology practices to reduce dental disease and improve oral health-related quality of life in head and neck cancer patients receiving radiation therapy. The key products and services to be delivered under this 1-year award include: 1) application of fluoride varnish by medical team members during post-radiation oncology follow-up visits, and 2) referral of patients with signs of dental disease or poor preventive dental care compliance to dental providers. The goal is to determine if this intervention, delivered in the oncology setting, can improve oral health outcomes and increase follow-up for this high-risk patient population compared to current standard oncology care practices.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $681.3k | 8/14/25 |