Cooperative Agreement U54CA302464
- This federal Project Grant award, with a total funding amount of $882,470, was provided by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to Baylor College of Medicine, a prestigious private non-profit health sciences university in Texas. The primary objective of this 5-year award is to expand the awardee's role as a leader in the design and conduct of NCI-funded clinical trials for children, adolescents, and young adults with cancer, particularly hematologic...
- The University of Southern California (USC) was awarded a $442,404 Project Grant (Federal Grant Award ID: R21CA274416) by the National Cancer Institute (NCI), under the NCI's "Cancer Cause and Prevention Research" program (CFDA 93.393). This funding supports a research project titled "Mitochondrial Dysfunction Underlies Treatment Related Hepatotoxicity in Hispanics with Acute Lymphoblastic Leukemia." The project aims to identify the underlying causes of treatment-related...
- The U.S. National Cancer Institute (NCI) has awarded a $3,480,276 Project Grant under the Cancer Treatment Research program (CFDA 93.395) to Seattle Children's Hospital, doing business as Seattle Children's Research Institute. The funding will support a 4-year research initiative to systematically uncover the genomic heterogeneity of pediatric and adolescent/young adult Philadelphia chromosome-positive (Ph+) and ABL-class Ph-like acute lymphoblastic leukemia (ALL). The overarching goals are to...
- This Cooperative Agreement award, funded by the National Cancer Institute (NCI) under the Cancer Centers Support Grants program (CFDA 93.397), supports a comprehensive research initiative focused on improving outcomes for lymphoma patients, particularly those from African American and Hispanic backgrounds. The $2,561,113 grant, awarded on August 22, 2025, will enable the University of Texas MD Anderson Cancer Center to leverage its extensive resources, including a large prospective lymphoma...
- This federal Project Grant award of $649,293 from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) aims to study healthcare utilization and outcomes across the cancer care continuum, with a focus on understanding the impact of social risk factors and screening among Latino patients. The 5-year project, awarded to Ochin, Inc., a nonprofit health IT collaborative in Oregon, will leverage a robust electronic health record database spanning over 2 million Latino...
- The National Cancer Institute (NCI), under the Cancer Biology Research federal grant program (CFDA 93.396), awarded a $530,106 Project Grant to the Children's Hospital Medical Center in Cincinnati, Ohio. The grant, awarded on September 11, 2025, supports research aimed at understanding and targeting polyamine metabolism in leukemia stem cells (LSCs) to improve outcomes for patients with acute myeloid leukemia (AML). The overarching goal is to develop LSC-directed therapies that can help overcome...
- This federal Project Grant award of $676,550 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports research to understand the impact of socioeconomic status (SES) and adversity on hematopoietic cell transplant (HCT) outcomes in pediatric patients with high-risk hematological malignancies. The primary goals are to: 1) quantify the association between donor and recipient SES with pediatric HCT outcomes, and 2) evaluate how donor and recipient SES...
- The federal Project Grant award titled "Investigating and Targeting NSD2 Mutation-Driven Leukemia Transformation" is funded by the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) in the amount of $484,405.00 with a performance period from September 1, 2025 to August 31, 2030. The grant was awarded to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, a private non-profit academic medical center in Pennsylvania. The project aims to...
- This Project Grant award of $434,993 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to Children's Hospital Los Angeles. The funding supports research using high-throughput sequencing of the immunoglobulin loci to develop refined risk stratification methods for pediatric B-cell acute lymphoblastic leukemia (B-ALL). The project aims to advance understanding and treatment of this pediatric cancer, with an expected completion...
- The National Cancer Institute (NCI) has awarded a Cooperative Agreement totaling $1,059,908 to St. Jude Children's Research Hospital Inc. under the Cancer Cause and Prevention Research program (CFDA 93.393). This funding supports the St. Jude Lifetime Cohort (SJLIFE) study, an unparalleled longitudinal research initiative established in 2007 to investigate health outcomes and premature mortality among over 10,000 survivors of childhood and adolescent cancer. Key products and services provided...
This $2,494,110 Cooperative Agreement was awarded on September 23, 2025 by the National Cancer Institute (NCI), under the federal Cancer Centers Support Grants program (CFDA 93.397). The grant aims to reduce ethnic disparities in outcomes for Latino children and adolescents with acute lymphoblastic leukemia (ALL) by identifying biological and social determinants of health factors contributing to adverse treatment-related toxicities and poor survival. The 5-year project will be administered by Baylor College of Medicine and includes four research projects to study hepatotoxicity, methotrexate-associated neurotoxicity, pharmacogenomics, and patient-reported outcomes, epigenetics, and social determinants of health related to ALL treatment in Latino populations. The award will fund the establishment of the first Specialized Programs of Research Excellence (SPORE) focused on pediatric leukemia, which will leverage administrative, biospecimen processing, statistical analysis, and community engagement cores to support the research objectives.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 9/22/25 |