Cooperative Agreement U01CA294415
- This federal Project Grant award for $227,941, provided by the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research), will fund the development and piloting of the "Cancer Care Companion" - an electronic health record (EHR) tool to improve information exchange and self-management for pediatric cancer patients and their families. The project aims to engage parents and pediatric oncology clinicians to co-develop the EHR-based communication tool, which will adapt...
- This Project Grant award for $616,710.00, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports the Children's Research Institute in Washington, D.C. in designing effective adoptive immunotherapy for high-risk pediatric medulloblastoma. The research aims to develop a rational combination with MRI-guided focused ultrasound technology to enhance this innovative cancer treatment approach. The award period runs from August 1, 2024...
- This Project Grant award of $696,133, provided by the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394), supports research to develop non-invasive imaging methodologies for tracking neural stem cells (NSCs) in the brains of mouse models bearing breast cancer brain metastases. The primary awardee, Northwestern University, will optimize an integrated single-photon emission microscope and magnetic resonance imaging system to enable high-resolution,...
- This Cooperative Agreement, awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research), provides $315,066 in funding to The Regents of the University of California, San Francisco (UCSF) from September 1, 2025 to August 31, 2028. The project aims to validate, translate, and clinically implement a gene expression biomarker to predict outcomes and radiotherapy responses for meningioma, a common type of brain tumor. The research will focus on improving risk...
- This $435,827 Project Grant from the National Cancer Institute (NCI) under the CFDA 93.394 Cancer Detection and Diagnosis Research program supports research conducted by New York University (NYU) School of Medicine to develop deep learning methods for analyzing mass spectrometry imaging (MSI) data. The goal is to make MSI data more accessible to existing machine learning workflows by expanding the dimensionality of the data structure to treat each metabolite or lipid as an individual "color...
- The National Cancer Institute (NCI) awarded a $164,639 Project Grant (CFDA 93.394 - Cancer Detection and Diagnosis Research) to Brown University to develop a novel pipeline for kidney segmentation and registration based on deep learning techniques. The goal is to improve treatment efficacy and reduce recurrence rates for image-guided thermal ablation (IGTA), a minimally invasive cancer treatment. Specifically, the research will focus on detecting and mitigating potentially undetected...
- The National Cancer Institute (NCI), through the Cancer Detection and Diagnosis Research federal grant program (CFDA 93.394), awarded a $244,839 project grant to the University of Virginia. The grant aims to investigate the potential of using magnetic resonance imaging-guided focused ultrasound (MRGFUS) to enhance the delivery and persistence of chimeric antigen receptor (CAR) T cell therapy for pediatric medulloblastoma, a common and challenging brain cancer in children. Under a sub-award,...
- This Project Grant award from the National Cancer Institute's (CFDA 93.394 - Cancer Detection and Diagnosis Research) will fund a research project titled "Innovative Scan Protocols with Combined Long Axial FOV PET and Spectral CT for Improved Quantification in Oncology". The $666,670 award, effective January 15, 2025, aims to develop advanced imaging protocols and processing techniques that utilize both positron emission tomography (PET) and spectral computed tomography (CT) to enhance...
- This $459,000 Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) supports research conducted by the New York Institute of Technology (NYIT) to gain crucial insights into the biology of choroid plexus tumors, with the goal of developing novel therapeutic strategies. The research aims to utilize accurate experimental models to better understand the differentiation and tumorigenesis of the choroid plexus, a critical structure within the brain....
- This Cooperative Agreement award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $481,052 to the Research Institute at Nationwide Children's Hospital to develop a preclinical/clinical pipeline to rapidly test new therapies for a deadly form of pediatric rhabdomyosarcoma (RMS) driven by mutant MYOD1. The primary goal is to identify effective treatments, including PI3K-targeted therapies, for this almost universally lethal malignancy by leveraging...
This Cooperative Agreement award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) will provide $398,532 to the University of Wisconsin-Madison to develop the Pediatric Brain Tumor Image Informatics (PBTI2) Toolkit. The project aims to create a unified, community-driven set of tools to improve prognostic modeling and risk-stratification for pediatric brain tumors using advanced imaging techniques like machine learning and deep learning. The key components of the toolkit include CUPED, a cohort curation tool, and companion prognostic models leveraging radiomics to capture unique tumor characteristics in pediatric brain scans. This work seeks to enable more personalized treatment approaches by identifying high-risk cases that may benefit from intensified therapy, while enabling therapy de-escalation for low/standard-risk patients. The project will be executed over a 3-year period from August 2025 to July 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $398.5k | 8/5/25 |