This Cooperative Agreement award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $406,352 to Harvard Medical School to identify optimal pre-analytical handling conditions for a functional precision medicine biomarker called RAMP up dynamic BH3 profiling (RUDBP). The goal is to systematically evaluate how different pre-analytical factors like tumor transport, frozen storage, and ex vivo cell culture impact the fidelity and output of the RUDBP biomarker, which can assess drug sensitivity in patient tumor cells. The 5-year project aims to establish best practices for pre-analytical tumor handling to minimize false results and accelerate the clinical adoption of functional precision medicine approaches for relapsed and refractory ovarian cancer patients.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $406.4k | 7/16/25 |