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Cooperative Agreement R43MH118180
Award Date
6/1/18
Completion Date
5/31/19
Dollars Obligated
$183K
Overview
Activity
Transactions
4
Subawards
1
Federal Agency
National Institute of Mental Health
Awardee
Qualia, Inc. (NYPMWLLW55D3)
Federal Grant Program
93.242
Assistance Type
Cooperative Agreement
Place of Performance
Dallas, TX 75252, USA
Description
Update #1
DYNAMICALLY SOFTENING IMPLANTABLE MICROELECTRODE ARRAYS
Posted 5/23/18, 12:00 AM
Mod #
Description
Reason For Modification
Federal Obligation
(Click to sort descending)
Date
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Not listed
DYNAMICALLY SOFTENING IMPLANTABLE MICROELECTRODE ARRAYS
$6.0k
1/29/20
Not listed
DYNAMICALLY SOFTENING IMPLANTABLE MICROELECTRODE ARRAYS
($6k)
12/4/19
Not listed
DYNAMICALLY SOFTENING IMPLANTABLE MICROELECTRODE ARRAYS
$0
3/27/19
Not listed
DYNAMICALLY SOFTENING IMPLANTABLE MICROELECTRODE ARRAYS
$182.7k
5/23/18
Grant Number
Description
Subgrantee
Prime Award
Dollars Obligated
(Click to sort descending)
Updated At
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1705954S
The University of Texas at Dallas (UT Dallas) shall provide support for design and testing of novel multi-shank microelectrode arrays comprised of shape memory polymers. UT Dallas will deliver detailed protocols, images and summarized data on all experiments to Qualia Inc. Task 1: Design array structures composed of SMP materials with optimized dimensions. Task 1A: UT Dallas shall test an initial design based on beam buckling and Euler s formula by insertion of probes into rat cortex. Initial device performance will be based on percentage of successful insertion without buckling in for n=20 devices. Task 1B: UT Dallas shall develop a 3D finite element model using COMSOL of the multi-shank array to determine buckling modes and critical loads associated with different geometries based on required penetration force measured during insertion experiments in Task 1A. With this modeling, UT Dallas shall examine the parameter space associated with shank length, thickness and probe pitch. UT Dallas shall prepare a report to Qualia Inc. documenting the methodology and findings for a recommended 3D architecture that meets the force requirements for reliable probe insertion. Task 1C: UT Dallas shall verify final design resistance to buckling with successful insertion of refined probes into rat cortex. At least 20 devices will be tested where success is defined as an absence of buckling in at least 90% of the trials. Task 2: In vitro characterization of multi-shank arrays. Following the fabrication of test devices, UT Dallas shall perform electrochemical stability measurements including impedance spectroscopy and cyclic voltammetry under accelerated aging conditions. No less than 6 replicate measurements shall be performed with at least 3 versions of the device architecture. Following completion of tests of each device architecture, UT Dallas shall report to Qualia Inc. on stability findings and provide documentation on all aspects of the methodology.
University Of Texas At Dallas
Cooperative Agreement R43MH118180
$45.7k
6/12/18