Project Grant R43CA235890

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded Cellia Science, Inc. a $1,074,143 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) on June 11, 2025. The grant supports the development of a point-of-care instrument for rapid, non-destructive assessment of bone marrow aspiration sample adequacy. The approach utilizes label-free, deep-ultraviolet (UV) microscopy combined with machine learning...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...

This $255,991 National Science Foundation project grant supports the development of an automated system for rapid analysis of biopsy samples by Amcyt, Inc. The system aims to increase the efficiency and accessibility of fine needle aspiration biopsy procedures through three automated processes: sample smearing, staining, and image capture. This addresses a critical need to improve biopsy analytics and potentially eliminate up to 20% of failed procedures due to sampling errors. By automating...

The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded The Johns Hopkins University a $395,566 Project Grant under the Engineering (47.041) federal grant program. The grant funds research to develop new optical and computational tools to improve histological imaging of unprocessed tissues without the need for tissue slides. Specifically, the grantee aims to create a novel macroscope projecting ultraviolet illumination at high spatial...

Visikol Inc. received a $4,103,265 Project Grant award from the National Cancer Institute, a division of the Department of Health and Human Services, under the Cancer Detection and Diagnosis Research program (CFDA 93.394). The award will support the development of a 3D imaging diagnostic tool to improve characterization of metastatic melanoma in sentinel lymph node biopsies. Visikol will conduct a retrospective clinical study using archived negative sentinel lymph node biopsy tissue blocks to...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $389,751 Project Grant under CFDA 93.286, "Discovery and Applied Research for Technological Innovations to Improve Human Health," to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant aims to develop a low-cost, compact holographic imaging-based microfluidic cell sorting system using 3D printing. The research will explore the use of 3D holographic...

This Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) is funding the development of the ORION2 instrument, a novel approach to acquiring highly multiplexed tissue images from formaldehyde fixed paraffin embedded (FFPE) specimens. The ORION2 instrument will use an "attention-based" imaging approach to focus on the most important or informative regions of a specimen, balancing speed of data acquisition and image...

This Project Grant award from the National Cancer Institute (CFDA 93.394, Cancer Detection and Diagnosis Research) provides $647,398 to the Regents of the University of Michigan to develop quantitative bone marrow MRI biomarkers to assess the efficacy of novel molecularly targeted agents for myelofibrosis. The 5-year project aims to apply advanced MRI techniques, including Dixon imaging, diffusion-weighted imaging, and magnetization transfer imaging, to monitor bone marrow changes in...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is providing $1,337,953.41 to the University of Arizona to develop and disseminate an advanced 2-photon Bessel beam light sheet (2PBLS) microscopy instrument for high-speed, sub-micron resolution volumetric imaging in deep tissue. The proposed instrument will enable faster...

The National Institutes of Health (NIH) awarded a $749,854 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Albany Medical College to acquire an Olympus FVMPE-RS multiphoton microscope for intravital microscopy research. This specialized microscope will enable NIH-supported investigators at Albany Medical College and other nearby research institutions to conduct detailed mechanistic studies using mouse models of disease, covering a range of research areas including...