The University of Illinois has received a $13,340,331 Cooperative Agreement award from the Department of the Interior's Interior Business Center under the Advanced Research Projects Agency for Health (ARPA-H) program (CFDA 93.384) to develop a multimodal, multiscale optical imaging platform for use in cancer surgery. The platform will utilize optical coherence tomography (OCT) and nonlinear optical (NLO) imaging to provide real-time digital histopathology during surgical procedures, with the goal of reducing positive margins, reoperation rates, and local recurrence in cancer patients. The project will involve collaboration with industry partners and experts in optical imaging, robotic surgery, and artificial intelligence. The award will fund the development and demonstration of this "MarginDx" platform solution over a 5-year period, with the aim of rapidly disseminating the technology to improve the standard of care for precision surgical interventions.
The project includes two federal grant sub-awards: one to Eleuthra Photonics, Inc. to support the development of the optical imaging and guidance technology, and another to Mayo Clinic to leverage their expertise in cancer research and drug development. These sub-awards will contribute to the overall objectives of the project by providing critical components and specialized knowledge to the University of Illinois-led effort.
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